Clonal (monoclonal)

Posted on December 5th, 2001 by

A population of cells derived from a single primitive cell. Virtually all neoplasms (an abnormal overgrowth of cells benign and malignant), are derived from a single cell with a DNA mutation, and thus, are clonal. The mutated primitive cell has an alteration in its DNA that forms an oncogene and leads to its transformation into a cancer-causing cell. The cancer is the total accumulation of cells that grow from the single mutated cell.

Tags: C, Cancer Dictionary

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