Translocation

Posted on December 5th, 2001 by

An abnormality of chromosomes in marrow or lymph node cells, which occurs when a piece of one chromosome breaks off and sticks to the end of another chromosome. In a balanced translocation, each of two chromosomes breaks off and the lost piece sticks to the broken end of the other chromosome. The gene at which the break occurs is altered. This is one form of a somatic mutation, which may transform the gene into an oncogene or cancer-causing gene.

Tags: Cancer Dictionary, T

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