October 20, 2009

Coffee Consumption May Reduce Risk of Uterine Cancer


Coffee consumption may reduce the incidence of uterine cancer, especially among overweight and obese women, according to the results of a study published in the International Journal of Cancer.[1]

Researchers continue to evaluate the link between dietary intake and cancer. Several studies have shown a reduced risk of uterine cancer associated with coffee consumption.[2][3][4] Although the reasons for this are unclear, some evidence suggests that coffee consumption may lower insulin resistance, which has been associated with uterine cancer.

Researchers used data from the Swedish Mammography Cohort, which was a population-based cohort study that involved 60,634 women who were followed for an average of 17.6 years. During that time, 677 women were diagnosed with uterine cancer. The women self reported their coffee consumption at baseline (between 1987 and 1990) and then again in 1997.

Each additional cup of coffee per day was associated with a 10% reduction in the risk of developing uterine cancer. Interestingly, the association appeared to be related to body mass index, as it was confined to women who were overweight or obese. Each additional cup of coffee resulted in a 12% risk reduction in overweight women and a 20% risk reduction in obese women.

The researchers concluded that coffee consumption might decrease the risk of uterine cancer, especially among women who are overweight or obese.


[1] Friberg E, Orsini N, Mantzoros CS, et al. Coffee drinking and risk of endometrial cancer – A population-based cohort study. International Journal of Cancer. 2009; 125:2413-2417.

[2] Bravi F, Scotti L, Bosetti C, et al. Coffee drinking and endometrial cancer risk: a meta-analysis of observational studies. American Journal of Obstetrics and Gynecology. 2009; 200:130-134.

[3] Shimazu T, Inoue M, Sasaxuki S, et al. Coffee consumption and risk of endometrial cancer: A prospective study in Japan. International Journal of Cancer. 2009; 123:2406-2410.

[4] McCann Se, Heh M, Rodabough K, et al. Higher regular coffee and tea consumption is associated with reduced endometrial cancer risk. International Journal of Cancer. 2009; 134: 1650-1653.

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Tags: Uncategorized, UNM CC Features