Posted on July 5th, 2011 by
Men who smoke at the time they’re diagnosed with prostate cancer have an increased risk of recurrence and death compared with never smokers. Odds for men who quit smoking at least 10 years previously, on the other hand, are similar to those of never smokers. These findings were recently reported in JAMA.
Evidence continues to mount of an association between lifestyle factors and health. Smoking is a commonly investigated behavior for its association with several forms of cancer as well as other disease and illnesses.
To date, studies evaluating a link between smoking and prostate cancer and recurrence have been limited, with even less research focusing on prostate cancer-specific outcomes.
To better investigate whether smoking affects outcomes for patients with prostate cancer, researchers with Harvard School of Public Health and University of California, San Francisco, evaluated 5,366 men diagnosed with prostate cancer between 1986 and 2006. The outcomes they measured included overall mortality, prostate cancer-specific mortality, death from cardiovascular disease, and biochemical recurrence (as indicated by a rise in PSA level).
Though findings of an increased risk among current smokers of death from all causes, prostate cancer, and cardiovascular disease as well as increased risk of biochemical recurrence are bad news for smokers, these data also provide good incentive to quit. It appears that men who have quit smoking for at least 10 years prior to prostate cancer diagnosis have risks similar to those of men who have never smoked.
Reference: Kenfield SA, Stampfer MJ, Chan JM, et al. Smoking and prostate cancer survival and recurrence. JAMA. 2011;305(24):2548-2555. doi: 10.1001/jama.2011.879.
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