Posted on February 11th, 2013 by
Class: Hormonal Therapy
Generic Name: dutasteride
Trade Names: Avodart®
How is this drug used? Avodart is used alone or in combination with another drug—tamsulosin—to treat symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Avodart is used to improve symptoms, reduce the risk of sudden inability to pass urine, and reduce the need for surgery related to BPH. Avodart is not approved for the prevention of prostate cancer.
What is the mechanism of action? Avodart lowers the levels of a hormone called dihydrotestosterone (DHT). DHT plays a role in prostate growth. Lowering DHT levels can cause the prostate to shrink.
How is Avodart given (administered)? Avodart is taken orally (by mouth).
How are patients monitored? Patients will usually have scheduled meetings with their healthcare provider while they are being treated with Avodart. Patients may also undergo physical examinations, blood tests, or other measures to assess side effects and response to therapy.
What are the most common side effects of treatment with Avodart?
What are some of the other potential side effects of Avodart?
This is not a complete list of side effects. Some patients may experience other side effects that are not listed here. Patients may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.
Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.
What can patients do to help alleviate or prevent discomfort and side effects?
Are there any special precautions patients should be aware of before starting treatment?
When should patients notify their physician? Tell your doctor if you experience any side effects that bother you or don’t go away. Also tell your doctor if you have signs of an allergic reaction (such as swelling of the face, tongue, or throat, or skin reactions) or breast changes such as lumps or nipple discharge.
What is a package insert?
A package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumers. A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug. By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. If you do not have the package insert for the drug you are using, your pharmacist or physician may be able to provide you with a copy.
Last updated on 09/16.
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