Enablex®

Posted on March 18th, 2013 by

Class: Other

Generic Name: Darifenacin

Trade Names: Enablex®

How is this drug used? Enablex is used to treat overactive bladder with symptoms of a strong need to urinate right away; leaking accidents due to a strong, immediate need to urinate; or a need to urinate often.

What is the mechanism of action? Enablex acts by relaxing the bladder muscles. It is a type of drug known as an anticholinergic.

How is Enablex given (administered)? Enablex is taken orally (by mouth).

How are patients monitored? Patients will usually have scheduled meetings with their healthcare provider while they are being treated with Enablex.  Patients may undergo physical examinations or other measures to assess side effects and response to therapy.

What are the most common side effects of treatment with Enablex? 

  • Dry mouth
  • Constipation
  • Headache
  • Heartburn
  • Nausea
  • Urinary tract infection
  • Blurred vision
  • Heat exhaustion or heat stroke in hot environments

What are some of the less common side effects of treatment with Enablex?

  • Serious allergic reactions

This is not a complete list of side effects. Some patients may experience other side effects that are not listed here. Patients may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.

Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.

What can patients do to help alleviate or prevent discomfort and side effects?

  • Pay careful attention to the physician’s instructions, and discuss side effects with your physician.
  • Do not drive or operate heavy machinery until you know how Enablex affects you.

Are there any special precautions patients should be aware of before starting treatment?

  • Enablex should not be taken by people who have trouble emptying their bladder, slow emptying of the stomach, uncontrolled narrow-angle glaucoma, or allergies to any of the ingredients in Enablex.
  • Patients should inform their physician about all medical conditions, including stomach or intestinal problems, constipation, weak urine stream or trouble emptying the bladder, narrow-angle glaucoma, kidney problems, or liver problems.
  • Patients should inform their physician of any other medication or supplement they are taking (whether prescription or over-the-counter), including antifungal medications, antibiotics, anti-HIV medications, antidepressant medications, antipsychotic medications, and medications used to treat an abnormal heartbeat.
  • Patients should tell their doctor if they are pregnant, breastfeeding, or planning to become pregnant. It is not known whether Enablex will harm an unborn baby.

When should patients notify their physician?

Tell your doctor if you experience any side effects that bother you or don’t go away. Seek immediate medical care if you notice signs of a serious allergic reaction, such as swelling of the face, lips, throat, or tongue; hives, skin rash, or swelling; severe itching, or trouble breathing.

What is a package insert?

A package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumers.  A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug. By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. If you do not have the package insert for the drug you are using, your pharmacist or physician may be able to provide you with a copy.

Copyright © 2016 CancerConnect Last updated 03/13.

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Tags: Drug Dictionary, E, Other

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