Items Tagged ‘Adjuvant (I-III, A-C) Colon Cancer’

July 28th, 2016

Addition of Eloxatin® Following Surgery Delays Cancer Progression in Certain Colorectal Cancers

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The addition of the chemotherapy combination consisting of Eloxatin (oxalipatin) plus 5-fluorouracil (5 FU) following surgery reduces the risk of cancer progression among patients with deficient mismatch repair (dMMR) stage III colorectal cancer. These results were recently published in the Journal of the National Cancer Institute. Among patients with colorectal cancer that has spread to […]

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Tags: 5fu, Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, colorectal cancer, crc, dmmr, eloxatin, mismatch repair, News, oxaliplatin, Rectal Cancer, Stages I-III Rectal Cancer


June 27th, 2016

Stent Placement Reduces Need for Stoma in Some Colorectal Cancers

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The placement of a stent as initial emergency treatment for colon obstruction reduces the need for a stoma without adversely affecting outcomes for patients with potentially curable colorectal cancer. These results were recently presented at the 2016 annual meeting of the American Society of Clinical Oncology (ASCO). Colorectal cancer remains the second leading cause of […]

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Tags: 2016, Adjuvant (I-III, A-C) Colon Cancer, asco, Colon Cancer, curable, News, obstruction, stent, stoma


January 28th, 2016

Vectibix® Improves Survival in Colorectal Cancer, Demonstrates Importance of Tissue Testing

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The addition of Vectibix® (panitumumab) to best supportive care improves survival over best standard care alone among colorectal cancer patients who have stopped responding to chemotherapy. However, the benefit is only seen with patients who have no RAS mutations, or those with only the KRAS exon 2 mutation. These results were recently presented at the […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, colorectal cancer, KRAS exon 2, News, panitumumab, Rectal Cancer, Recurrent/Relapsed Rectal Cancer, Stage IV (D)/Relapsed Colon Cancer, Stage IV Rectal Cancer, Stages I-III Rectal Cancer, vectibix


September 29th, 2014

Advances in Genomic Testing-What you Need to Know

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Q: What is genomic testing? A: Genomic testing looks at a group of genes and their varying levels of expression. This gene expression or activity can characterize how genes interact with one another and predict the behavior of certain tissues within the body. This is in contrast to genetic testing, which looks at a specific change […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Breast Cancer, Colon Cancer, Early Stage I-II (A-B) Prostate Cancer, General, genomics, News, Other News Topics (not Types of Cancer), Prostate Cancer, Stage I Node Negative Breast Cancer


September 22nd, 2014

Oncotype DX Colon Cancer Test May Reduce Medical Costs Associated with Stage II Disease While Increasing Patient Well-being

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REDWOOD CITY, Calif., Sept. 12, 2014 /PRNewswire/ – Genomic Health, Inc. (Nasdaq: GHDX) today announced that PharmacoEconomics published positive results from a health economic analysis suggesting that use of the Oncotype® DX colon cancer test may result in a significant reduction in direct medical costs and improve patient quality of life by helping them avoid side effects of unnecessary treatment. “By […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, early stage colon cancer, genomics, News, oncotype, stage 2 colon cancer


August 26th, 2014

Doctors find that Cholesterol Lowering Statin Drugs may Improve Survival From Colon Cancer

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According to a new U.K. study, statins, which are widely used cholesterol-lowering drugs, appear to improve colon cancer survival.  The study found that overall, colon cancer patients who took statins such as Lipitor and Zocor had a 29 percent lower risk of dying from their cancer compared to non-users.(1) According to estimates from the American Cancer […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News, Screening/Prevention Colon Cancer, Stage IV (D)/Relapsed Colon Cancer, statins


August 20th, 2014

Exercise & Diet Rich in Fish May Help Prevent Colon Cancer’s Return

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A new study suggests that regular exercise and a diet that includes fish may help colon cancer patients improve their odds of avoiding a cancer recurrence. (1) The likelihood that patients will suffer a return of colon cancer more than doubles if they eat fish less than twice a week, or if they get less […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, diet, News, nutrition, recurrence, Screening/Prevention Colon Cancer, Stage IV (D)/Relapsed Colon Cancer


July 2nd, 2014

Study Shows Polypectomy as Effective as Partial Colon Resection

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A team from Stony Brook University reported that patients requiring removal of colon polyps could be effectively treated with laparoscopic-assisted polypectomy (LACP) and that the procedure required fewer resources than did partial colon resection (laparoscopic hemicolectomy, LHC), a common treatment for these patients. In this randomized study presented at the 2014 Digestive Disease Week (DDW) […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News, polypectomy, prevention, screening, Screening/Prevention Colon Cancer, surgery


January 15th, 2014

Oncotype Validated in Stage II and III Colon Cancer

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The Oncotype DX® Recurrence Score® (RS) results predict recurrence risk in stage II and III colon cancer and may better inform adjuvant therapy decisions in this population, according to the results of a validation study published in the Journal of Clinical Oncology. Stage II colon cancer refers to cancer that extends through the wall of […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


December 26th, 2013

Oncotype DX Changes Treatment Recommendations in Stage II Colon Cancer

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Use of the Oncotype DX® colon cancer test changed treatment recommendations in 29 percent of stage II colon cancer patients, according to the results of a study published in Current Medical Research and Opinion. Stage II colon cancer refers to cancer that extends through the wall of the colon but has not invaded lymph nodes […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


June 14th, 2013

Genomic Testing May Reduce Medical Costs for Colon Cancer

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Use of the Oncotype DX® colon cancer test to guide treatment decisions may reduce medical costs and improve patient well-being. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). The Oncotype DX colon cancer test evaluates 12 genes in a sample of tumor tissue and generates a […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


April 22nd, 2013

Second Large Study Confirms Oncotype DX Can Predict Recurrence in Stage 2 Colon Cancer

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Results from the large CALGB 9581 clinical validation study of the Oncotype DX® colon cancer test confirm that Recurrence Score® (RS) results improve the ability to differentiate high recurrence risk disease from low recurrence risk disease, beyond conventional factors such as T-stage, mismatch repair (MMR) status, nodes examined, grade and lymphovascular invasion. The results of […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


February 20th, 2013

Oncotype DX in Colon Cancer May Reduce Medical Costs and Improve Patient Wellbeing

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The results of two studies evaluating Oncotype DX were presented at the 2013 Gastrointestinal Cancers Symposium in San Francisco and the data indicated that the colon cancer test may reduce medical costs, improve patient wellbeing, and change treatment recommendations. Gene expression profiling explores the patterns of genes that are active in tumor cells. Studies suggest […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


January 3rd, 2013

Oncotype Validated in Stage II and III Colon Cancer

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The Oncotype DX® Recurrence Score® (RS) results predict recurrence risk in stage II and III colon cancer and may better inform adjuvant therapy decisions in this population, according to the results of a validation study published in the Journal of Clinical Oncology. Stage II colon cancer refers to cancer that extends through the wall of […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News


November 6th, 2012

Aspirin May Prolong Life in PIK3CA-Mutated Colorectal Cancers

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Daily aspirin use improves survival among patients with mutated-PIK3CA colorectal cancer, according to the results of a study published in the New England Journal of Medicine. Colorectal cancer remains the second leading cause of cancer-related death in the United States. The phosphatidylinositol 3-kinase (PI3K) signaling pathway plays a significant role in carcinogenesis. Approximately 15 to 20 […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, News, Rectal Cancer, Recurrent/Relapsed Rectal Cancer, Screening/Prevention Colon Cancer, Screening/Prevention Rectal Cancer, Stage IV (D)/Relapsed Colon Cancer, Stage IV Rectal Cancer, Stages I-III Rectal Cancer