Items Tagged ‘Alphabetical Sort’

November 14th, 2014

Afatinib

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Class: Biological Therapy Generic Name: afatinib Trade Name: Gilotrif® For which conditions is this drug approved? Gilotrif is approved for first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have the following epidermal growth factor receptor (EGFR) traits: exon 19 deletions or exon 21 (L858R) substitution mutations. Exons are the protein-coding DNA […]

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Tags: A, Alphabetical Sort, Biological Therapy, Drug Dictionary


November 14th, 2014

Gilotrif®

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Class: Biological Therapy Generic Name: afatinib Trade Name: Gilotrif® For which conditions is this drug approved? Gilotrif is approved for first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have the following epidermal growth factor receptor (EGFR) traits: exon 19 deletions or exon 21 (L858R) substitution mutations. Exons are the protein-coding DNA […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, G


November 14th, 2014

Keytruda®

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Class: Biological Therapy Generic Name: Pembrolizumab Trade Name: Keytruda® For which conditions is this drug approved? Keytruda is approved for: a) initial treatment of metastatic melanoma, melanoma that is unresectable and metastatic melanoma with disease progression following treatment with Yervoy® (ipilimumab) and, if BRAF V600 mutation positive, treatment with a BRAF inhibitor, b) treatment of […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, K


November 14th, 2014

pembrolizumab

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Class: Biological Therapy Generic Name: Pembrolizumab Trade Name: Keytruda® For which conditions is this drug approved? Keytruda is approved for: a) initial treatment of metastatic melanoma, melanoma that is unresectable and metastatic melanoma with disease progression following treatment with Yervoy® (ipilimumab) and, if BRAF V600 mutation positive, treatment with a BRAF inhibitor, b) treatment of metastatic […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, P


October 24th, 2014

Trametinib

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Class: Biological Therapy Generic Name:Trametinib Trade Name:MEKINIST® For which conditions is this drug approved? MEKINIST is indicated for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic melanoma with a specific type of BRAF mutation (BRAF V600E or V600K), as detected by an FDA-approved test. What is the mechanism of […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, T


October 24th, 2014

MEKINIST®

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Class: Biological Therapy Generic Name:Trametinib Trade Name:MEKINIST® For which conditions is this drug approved? MEKINIST is indicated for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic melanoma with a specific type of BRAF mutation (BRAF V600E or V600K), as detected by an FDA-approved test. What is the mechanism of […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, M


October 24th, 2014

TAFINLAR®

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Class: Biological Therapy Generic Name:Dabrafenib Trade Name:TAFINLAR® For which conditions is this drug approved? TAFINLAR isindicated as a single agent for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic melanoma with BRAF V600E mutation, as detected by an FDA-approved test. TAFINLAR is also indicated in combination with MEKINIST® (trametinib) […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, T


October 24th, 2014

Dabrafenib

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Class: Biological Therapy Generic Name:Dabrafenib Trade Name:TAFINLAR® For which conditions is this drug approved? TAFINLAR isindicated as a single agent for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic melanoma with BRAF V600E mutation, as detected by an FDA-approved test. TAFINLAR is also indicated in combination with MEKINIST® (trametinib) […]

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Tags: Alphabetical Sort, Biological Therapy, D, Drug Dictionary


October 21st, 2014

IMBRUVICA®

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Generic Name:  Ibrutinib Trade Name:  IMBRUVICA® For which conditions is this drug approved? IMBRUVICA is indicated for treatment of mantle cell lymphoma (MCL) for chronic lymphocytic leukemia (CLL), both in patients who have received at least one prior therapy;  and for Waldenström’s macroglobulinemia. What is the mechanism of action? IMBRUVICA is a tyrosine kinase inhibitor. These drugs […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, I


October 21st, 2014

Ibrutinib

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Generic Name:  Ibrutinib Trade Name:  IMBRUVICA® For which conditions is this drug approved? IMBRUVICA is indicated for treatment of mantle cell lymphoma (MCL) for chronic lymphocytic leukemia (CLL), both in patients who have received at least one prior therapy; and for Waldenström’s macroglobulinemia. What is the mechanism of action? IMBRUVICA is a tyrosine kinase inhibitor. These drugs work […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, I


April 23rd, 2014

Injectafer®

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Class: Supportive Care Generic Name: ferric carboxymaltose (FER-ik kar-box-ee-MAWL-tose) injection Trade Name: Injectafer® For which conditions is this drug approved? Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: Who have intolerance to oral iron or have had unsatisfactory response to oral iron Who have non-dialysis dependent chronic kidney disease What […]

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Tags: Alphabetical Sort, Drug Dictionary, I, Supportive


April 23rd, 2014

Injectafer®

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Class: Supportive Care Generic Name: ferric carboxymaltose (FER-ik kar-box-ee-MAWL-tose) injection Trade Name: Injectafer® For which conditions is this drug approved? Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: Who have intolerance to oral iron or have had unsatisfactory response to oral iron Who have non-dialysis dependent chronic kidney disease What […]

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Tags: Alphabetical Sort, Drug Dictionary, I, Supportive


July 31st, 2013

Mekinist ®

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Class: Biological Therapy Generic Name: trametinib Trade Name: Mekinist ® How is this drug used? Mekinist is used for the treatment of melanoma that has metastasized or cannot surgically removed and that tests positive for certain mutations (V600E or V600K) in the BRAF gene. What is the mechanism of action? BRAF gene mutations are common […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, M


July 31st, 2013

Trametinib

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Class: Biological Therapy Generic Name: trametinib Trade Name: Mekinist ® How is this drug used? Mekinist is used for the treatment of melanoma that has metastasized or cannot surgically removed and that tests positive for certain mutations (V600E or V600K) in the BRAF gene. What is the mechanism of action? BRAF gene mutations are common […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, T


July 16th, 2013

Tafinlar ®

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Class: Biological Therapy Generic Name: dabrafenib Trade Name: Tafinlar ® How is this drug used? Tafinlar is used for the treatment of melanoma that has metastasized or cannot surgically removed and that tests positive for a specific mutation (V600E) in the BRAF gene. What is the mechanism of action? Approximately half of all late-stage melanomas […]

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Tags: Alphabetical Sort, Biological Therapy, Drug Dictionary, T