Items Tagged ‘Biological Therapy’

June 8th, 2016

Tecentriq™

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Class: Biological Therapy Generic Name: Atezolizumab Trade Name: Tecentriq™ How is this drug used? Tecentriq is approved for patients with advanced urothelial carcinoma (bladder cancer) whose disease has progressed during or following therapy with a platinum agent. What is the mechanism of action? Tecentriq is an agent that creates its anti-cancer effects by blocking a specific protein, PD-L1, that is […]

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Tags: Biological Therapy, Drug Dictionary, T


June 8th, 2016

Atezolizumab

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Class: Biological Therapy Generic Name: Atezolizumab Trade Name: Tecentriq™ How is this drug used? Tecentriq is approved for patients with advanced urothelial carcinoma (bladder cancer) whose disease has progressed during or following therapy with a platinum agent. What is the mechanism of action? Tecentriq is an agent that creates its anti-cancer effects by blocking a specific protein, PD-L1, that is […]

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Tags: A, Biological Therapy, Drug Dictionary


May 17th, 2016

Praxbind®

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Class: Biologic Therapy Generic Name: idarucizumab Trade Name: Praxbind For which conditions is this drug approved? Praxbind® is indicated for patients specifically treated with Pradaxa® (dabigatran etexilate mesylate), an anti-clotting agent, when reversal of the anti-clotting effects of the agent is needed for emergency procedures, life-threatening instances, or uncontrolled bleeding. What is the mechanism of action?  Praxbind is a […]

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Tags: Biological Therapy, Drug Dictionary, P


May 17th, 2016

idarucizumab

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Class: Biologic Therapy Generic Name: idarucizumab Trade Name: Praxbind For which conditions is this drug approved? Praxbind® is indicated for patients specifically treated with Pradaxa® (dabigatran etexilate mesylate), an anti-clotting agent, when reversal of the anti-clotting effects of the agent is needed for emergency procedures, life-threatening instances, or uncontrolled bleeding. What is the mechanism of action?  Praxbind is a […]

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Tags: Biological Therapy, Drug Dictionary, I


May 12th, 2016

Venclexta®

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Class: Biological Therapy Generic Name: Venetoclax Trade Name: Venclexta® How is this drug used? Venclexta is approved for the treatment of patients with chronic lymphocytic leukemia (CLL) who have a specific chromosomal abnormality, referred to as a 17p deletion. Patients must have received at least one prior therapeutic regimen before starting treatment with Venclexta. What is the mechanism of […]

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Tags: Biological Therapy, Drug Dictionary, V


May 12th, 2016

Venetoclax

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Class: Biological Therapy Generic Name: Venetoclax Trade Name: Venclexta® How is this drug used? Venclexta is approved for the treatment of patients with chronic lymphocytic leukemia (CLL) who have a specific chromosomal abnormality, referred to as a 17p deletion. Patients must have received at least one prior therapeutic regimen before starting treatment with Venclexta. What is the mechanism of […]

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Tags: Biological Therapy, Drug Dictionary, V


May 12th, 2016

Cabometyx™

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Class: Biological Therapy Generic Name: Cabozantinib Trade Name: Cabometyx™ How is this drug used? Cabometyx is approved for patients with advanced renal cell carcinoma (RCC) who have already been treated with prior anti-angiogenic therapy. What is the mechanism of action? Cabometyx is a kinase inhibitor that binds to certain protein receptors on cells known as MET, AXL, and VEGFR-1, -2, […]

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Tags: Biological Therapy, C, Drug Dictionary


May 12th, 2016

Cabozantinib

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Class: Biological Therapy Generic Name: Cabozantinib Trade Name: Cabometyx™ How is this drug used? Cabometyx is approved for patients with advanced renal cell carcinoma (RCC) who have already been treated with prior anti-angiogenic therapy. What is the mechanism of action? Cabometyx is a kinase inhibitor that binds to certain protein receptors on cells known as MET, AXL, and VEGFR-1, -2, […]

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Tags: Biological Therapy, C, Drug Dictionary


May 6th, 2016

Crizotinib

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Class: Biological Therapy Generic Name: Crizotinib Trade Name: Xalkori® How is this drug used? Xalkori is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors test positive for an abnormality in the anaplastic lymphoma kinase (ALK) gene, or whose tumors are  ROS1-positive. What is the mechanism of action? Between one […]

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Tags: Biological Therapy, C, Drug Dictionary


April 6th, 2016

Imlygic™

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Class: Viral Therapy Generic Name: talimogene laherparepvec Trade Name: Imlygic™ For which conditions is this drug approved? Imlygic can be used to treat melanomas in the skin or lymph nodes that can’t be removed with surgery. What is the mechanism of action?  Imlygic is a herpes germ that has been altered to infect and kill cancer cells. These altered […]

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Tags: Biological Therapy, Drug Dictionary, I


April 6th, 2016

talimogene laherparepvec

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Class: Viral Therapy Generic Name: talimogene laherparepvec Trade Name: Imlygic™ For which conditions is this drug approved? Imlygic can be used to treat melanomas in the skin or lymph nodes that can’t be removed with surgery. What is the mechanism of action?  Imlygic is a herpes germ that has been altered to infect and kill cancer cells. These altered […]

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Tags: Biological Therapy, Drug Dictionary, T


April 6th, 2016

Cotellic™

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Class: Biological Therapy Generic Name: cobimetinib Trade Name: Cotellic™ For which conditions is this drug approved? Cotellic is a kinase inhibitor used for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with Zelboraf (vemurafenib). What is the mechanism of action?  A series of proteins called the MAPK cell signaling […]

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Tags: Biological Therapy, C, Drug Dictionary


April 6th, 2016

cobimetinib

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Class: Biological Therapy Generic Name: cobimetinib Trade Name: Cotellic™ For which conditions is this drug approved? Cotellic is a kinase inhibitor used for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with Zelboraf (vemurafenib). What is the mechanism of action?  A series of proteins called the MAPK cell signaling […]

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Tags: Biological Therapy, C, Drug Dictionary


March 28th, 2016

Tagrisso

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Class: Biological Therapy Generic Name: Osimertinib Trade Name: Tagrisso™ For which conditions is this drug approved? Tagrisso is a kinase inhibitor used to treat patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC) whose cancer has progressed on or after EGFR tyrosine kinase inhibitor therapy. What is the mechanism of action? Some non-small […]

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Tags: Biological Therapy, Drug Dictionary, T


March 28th, 2016

Osimertinib

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Class: Biological Therapy Generic Name: Osimertinib Trade Name: Tagrisso™ For which conditions is this drug approved? Tagrisso is a kinase inhibitor used to treat patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC) whose cancer has progressed on or after EGFR tyrosine kinase inhibitor therapy. What is the mechanism of action? Some non-small […]

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Tags: Biological Therapy, Drug Dictionary, O