Items Tagged ‘BRAF’

March 15th, 2017

COMBI-v BRAF/MEK Inhibitor Combination Trial Continues to Impress in Melanoma

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For advanced melanoma patients with BRAF mutations, two pathway inhibitors are much better than one, according to a study presented at the European Society for Medical Oncology.  The latest data confirm an estimated 45% of patients who received Tafinlar (dabrafenib) + Mekinist (trametinib) combination therapy are alive versus 31% of patients on BRAF monotherapy with […]

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Tags: BRAF, mek, Mekinist (trametinib), Melanoma, News, Tafinlar (dabrafenib), Zelboraf (vemurafenib


October 7th, 2015

Zelboraf® Appears Active in Hairy Cell Leukemia That Has Progressed After Other Treatment

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The medication Zelboraf® (vemurafenib) appears active in the treatment of hairy cell leukemia (HCL) that had progressed after previous therapy. These findings were published in New England Journal of Medicine. Hairy cell leukemia is a rare type of leukemia, or cancer of the immune cells. In HCL, the bone marrow makes too many lymphocytes (a […]

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Tags: BRAF, Hairy Cell Leukemia, HCL, Leukemia, News, vemurafenib, zelboraf


October 2nd, 2014

BRAF/MEK Inhibitor Combination Impressive in Melanoma Trials

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For advanced melanoma patients with BRAF mutations, two pathway inhibitors are much better than one, according to a study presented at the European Society for Medical Oncology Meeting this week. Of the more than one million new diagnoses of skin cancer each year, roughly 68,000 involve melanoma. More than 8,000 people die of melanoma each […]

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Tags: BRAF, cobimetinib, cobrim, mek, Melanoma, News, Recurrent Melanoma, Stage III Melanoma, Stage IV Melanoma, vemurafenib, zelboraf