Items Tagged ‘Drug Dictionary’

August 11th, 2016

fluorouracil

By

Class: Chemotherapy   Generic Name: fluorouracil (fler-oh-YOO-rah-sil), 5-FU, 5-fluorouracil Trade Name: Adrucil®, Carac®, Efudex® and Fluoroplex® For which conditions is this drug approved? Fluorouracil is FDA approved for the treatment of the following conditions: anal cancer, cervical cancer, colon cancer, rectal cancer, breast cancer, stomach (gastric) cancer, head and neck cancer, bladder cancer, neuroendocrine tumors, […]

View full entry

Tags: Chemotherapy, Drug Dictionary, F


June 8th, 2016

Tecentriq™

By

Class: Biological Therapy Generic Name: Atezolizumab Trade Name: Tecentriq™ How is this drug used? Tecentriq is approved for patients with advanced urothelial carcinoma (bladder cancer) whose disease has progressed during or following therapy with a platinum agent. What is the mechanism of action? Tecentriq is an agent that creates its anti-cancer effects by blocking a specific protein, PD-L1, that is […]

View full entry

Tags: Biological Therapy, Drug Dictionary, T


June 8th, 2016

Atezolizumab

By

Class: Biological Therapy Generic Name: Atezolizumab Trade Name: Tecentriq™ How is this drug used? Tecentriq is approved for patients with advanced urothelial carcinoma (bladder cancer) whose disease has progressed during or following therapy with a platinum agent. What is the mechanism of action? Tecentriq is an agent that creates its anti-cancer effects by blocking a specific protein, PD-L1, that is […]

View full entry

Tags: A, Biological Therapy, Drug Dictionary


May 17th, 2016

Praxbind®

By

Class: Biologic Therapy Generic Name: idarucizumab Trade Name: Praxbind For which conditions is this drug approved? Praxbind® is indicated for patients specifically treated with Pradaxa® (dabigatran etexilate mesylate), an anti-clotting agent, when reversal of the anti-clotting effects of the agent is needed for emergency procedures, life-threatening instances, or uncontrolled bleeding. What is the mechanism of action?  Praxbind is a […]

View full entry

Tags: Biological Therapy, Drug Dictionary, P


May 17th, 2016

idarucizumab

By

Class: Biologic Therapy Generic Name: idarucizumab Trade Name: Praxbind For which conditions is this drug approved? Praxbind® is indicated for patients specifically treated with Pradaxa® (dabigatran etexilate mesylate), an anti-clotting agent, when reversal of the anti-clotting effects of the agent is needed for emergency procedures, life-threatening instances, or uncontrolled bleeding. What is the mechanism of action?  Praxbind is a […]

View full entry

Tags: Biological Therapy, Drug Dictionary, I


May 12th, 2016

Defitelio®

By

Class: Supportive Care Generic Name: Defibrotide sodium Trade Name: Defitelio® For which conditions is this drug approved? Defitelio is used to treat severe hepatic veno-occlusive disease (VOD) in patients undergoing hematopoietic stem-cell transplantation (HSCT.) Hepatic VOD is a rare, but life-threatening complication that can occur following chemotherapy and a stem cell transplant as treatment for cancer. Hepatic VOD […]

View full entry

Tags: D, Drug Dictionary, Supportive


May 12th, 2016

Defibrotide sodium

By

Class: Supportive Care Generic Name: Defibrotide sodium Trade Name: Defitelio® For which conditions is this drug approved? Defitelio is used to treat severe hepatic veno-occlusive disease (VOD) in patients undergoing hematopoietic stem-cell transplantation (HSCT.) Hepatic VOD is a rare, but life-threatening complication that can occur following chemotherapy and a stem cell transplant as treatment for cancer. Hepatic VOD […]

View full entry

Tags: D, Drug Dictionary, Supportive


May 12th, 2016

Venclexta®

By

Class: Biological Therapy Generic Name: Venetoclax Trade Name: Venclexta® How is this drug used? Venclexta is approved for the treatment of patients with chronic lymphocytic leukemia (CLL) who have a specific chromosomal abnormality, referred to as a 17p deletion. Patients must have received at least one prior therapeutic regimen before starting treatment with Venclexta. What is the mechanism of […]

View full entry

Tags: Biological Therapy, Drug Dictionary, V


May 12th, 2016

Venetoclax

By

Class: Biological Therapy Generic Name: Venetoclax Trade Name: Venclexta® How is this drug used? Venclexta is approved for the treatment of patients with chronic lymphocytic leukemia (CLL) who have a specific chromosomal abnormality, referred to as a 17p deletion. Patients must have received at least one prior therapeutic regimen before starting treatment with Venclexta. What is the mechanism of […]

View full entry

Tags: Biological Therapy, Drug Dictionary, V


May 12th, 2016

Cabometyx™

By

Class: Biological Therapy Generic Name: Cabozantinib Trade Name: Cabometyx™ How is this drug used? Cabometyx is approved for patients with advanced renal cell carcinoma (RCC) who have already been treated with prior anti-angiogenic therapy. What is the mechanism of action? Cabometyx is a kinase inhibitor that binds to certain protein receptors on cells known as MET, AXL, and VEGFR-1, -2, […]

View full entry

Tags: Biological Therapy, C, Drug Dictionary


May 12th, 2016

Cabozantinib

By

Class: Biological Therapy Generic Name: Cabozantinib Trade Name: Cabometyx™ How is this drug used? Cabometyx is approved for patients with advanced renal cell carcinoma (RCC) who have already been treated with prior anti-angiogenic therapy. What is the mechanism of action? Cabometyx is a kinase inhibitor that binds to certain protein receptors on cells known as MET, AXL, and VEGFR-1, -2, […]

View full entry

Tags: Biological Therapy, C, Drug Dictionary


May 10th, 2016

Halaven®

By

Class: Chemotherapy Generic Name: Eribulin Trade Name: Halaven® For which conditions is this drug approved? Halaven is approved for metastatic breast cancer patients who have had at least two chemotherapy regimens for metastatic disease, including an anthracycline and a taxane. It is also indicated for patients with unresectable or metastatic liposarcoma who have received a prior regimen that includes […]

View full entry

Tags: Chemotherapy, Drug Dictionary, H


May 10th, 2016

Eribulin

By

Class: Chemotherapy Generic Name: Eribulin Trade Name: Halaven® For which conditions is this drug approved? Halaven is approved for metastatic breast cancer patients who have had at least two chemotherapy regimens for metastatic disease, including an anthracycline and a taxane. It is also indicated for patients with unresectable or metastatic liposarcoma who have received a prior regimen that includes […]

View full entry

Tags: Chemotherapy, Drug Dictionary, E


May 6th, 2016

Crizotinib

By

Class: Biological Therapy Generic Name: Crizotinib Trade Name: Xalkori® How is this drug used? Xalkori is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors test positive for an abnormality in the anaplastic lymphoma kinase (ALK) gene, or whose tumors are  ROS1-positive. What is the mechanism of action? Between one […]

View full entry

Tags: Biological Therapy, C, Drug Dictionary


April 19th, 2016

eltrombopag

By

Class: Supportive Care Generic Name: eltrombopag Trade Name: Promacta® How is this drug used? Promacta is used to treat thrombocytopenia (low platelet counts) in adult patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to other treatments. It is also used to treat thrombocytopenia in patients with chronic hepatitis C to allow for […]

View full entry

Tags: Drug Dictionary, E, Supportive