Items Tagged ‘glioblastoma’

May 23rd, 2016

Genetically Modified Poliovirus Granted “Breakthrough” by FDA for Glioblastoma

By

The United States Food and Drug Administration (FDA) has granted “breakthrough status” designation for the treatment of glioblastoma containing a genetically modified poliovirus. Glioblastoma is an extremely aggressive form of brain cancer, with few patients surviving 5 years following diagnosis. Despite efforts with surgery, chemotherapy, and/or radiation therapy, the overall outcomes for patients with glioblastoma […]

View full entry

Tags: Brain Cancer, breakthrough status, fda, General Brain Cancer, genetically modified polio virus, glioblastoma, immunotherapy, News


May 12th, 2016

Avastin®/Camptosar® Improves Outcomes Compared with Temodar® in Glioblastoma

By

The treatment combination consisting of Avastin (bevacizumab) plus Camptosar (irinotecan) improves time to cancer progression compared to treatment with Temodar (temozolomide) in patients with newly diagnosed glioblastoma. These results were recently published in the Journal of Clinical Oncology. Glioblastoma is an extremely aggressive form of brain cancer. Standard therapy includes surgery to remove as much […]

View full entry

Tags: avastin, bevacizumab, Brain Cancer, Campostar, glioblastoma, irinotecan, News, nonmethylated O6-methylguanine–DNA methyltransferase promotor, Temodar, temozolomide


February 17th, 2016

Immune Therapy for Brain Tumors: A New Promising Avenue

By

  Glioblastoma is a particularly aggressive type of brain cancer. Only about one fifth of adults diagnosed with it survive two years or more after their diagnosis. A new two-drug combination, currently in early clinical trials, might help people diagnosed with glioblastoma to fight the disease. In a presentation of early clinical trial data to […]

View full entry

Tags: Brain Cancer, clinical trial, glioblastoma, immune inhibitor, indoximod, News, temozolomide, UNM CCC


February 3rd, 2015

Danish Study Suggests Contraceptive Use Increases Risk of Brain Cancer

By

The results of a recently published clinical study suggest that taking the birth control pill for at least five years may double the risk of developing a glioblastoma multiforme (GBM), a rare but often fatal from of brain cancer. Glioblastoma multiforme is one of the most common and fatal types of primary brain cancer. It […]

View full entry

Tags: birth control, Brain Cancer, cancer risk, contraceptive, gbm, General Brain Cancer, glioblastoma, glioblastoma multiforme, News


September 19th, 2014

DNAtrix Announces Treatment Of First Patient With DNX-2401 In Recurrent Glioblastoma Trial

By

DNAtrix, Inc., experts in oncolytic virus development, today announced that the first patient was treated with the company’s lead product, DNX-2401, a replication competent adenovirus plus gamma interferon in a randomized, multicenter, open-label Phase Ib study for patients with recurrent glioblastoma. “DNAtrix, in collaboration with leading neurosurgeons and neuro-oncologists in the US, is pleased to […]

View full entry

Tags: adenovirus, Brain Cancer, dnx-2401, gamma interferon, gbm, General Brain Cancer, glioblastoma, News, recurrent glioblastoma


June 24th, 2014

Chemotherapy Following Radiation Improves Outcomes in Low Grade Glioblastoma

By

According to results recently presented at the 2014 annual meeting of the American Society of Clinical Onoclogy, patients with low-grade glioblastom multiforme (GBM) benefited from chemotherapy following radiation therapy compared to radiation therapy alone. consisting of procarbazine, CCNU, and vincristine (PCV) administered following radiation therapy improved progression-free survival and overall survival in adults with low-grade […]

View full entry

Tags: Brain Cancer, gbm, General Brain Cancer, glioblastom multiforme, glioblastoma, News