Items Tagged ‘HBOC’

October 2nd, 2013

Young Women Overestimate Risk of Secondary Breast Cancer

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Young women with breast cancer often overestimate their risk of developing cancer in the other breast—and also tend to overestimate the protective effect of removing the second breast, according to the results of a study published in the Annals of Internal Medicine. Approximately 200,000 women are diagnosed with breast cancer every year in the United […]

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Tags: Breast Cancer, Carcinoma In Situ Breast cancer, HBOC, Inflammatory Breast Cancer, Metastatic Breast Cancer, News, Recurrent Breast Cancer, Screening/Prevention Breast Cancer, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, Supportive Care Breast Cancer


August 23rd, 2013

BRCA Carriers on Tamoxifen Have Lower Risk of Second Cancer

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Women with BRCA1 or 2 mutations had fewer second, contralateral breast cancers while on tamoxifen for secondary prevention, according to the results of a study published in the Journal of Clinical Oncology. Some women who have been diagnosed with breast cancer will eventually develop a second breast cancer in the opposite breast. This is referred […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


July 31st, 2013

ASCO Updates Guidelines on Interventions for Women at Increased Risk of Breast Cancer

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The American Society of Clinical Oncology (ASCO) has released updated guidelines for pharmacologic interventions among women at an increased risk of breast cancer. This third update of the guidelines, published in the Journal of Clinical Oncology, includes the addition of Aromasin® (exemestane) for the prevention of breast cancer in postmenopausal women at risk for estrogen […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


June 10th, 2013

Gene Mutations Common In African American Women with Triple-Negative or Early Onset Breast Cancer

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Among African-American women with breast cancer referred for genetic counseling, one in five had an inherited mutation in at least one of the 18 genes that are linked with breast cancer susceptibility. The frequency of gene mutations was even higher in certain subgroups of these women. These results were presented at the 2013 Annual Meeting […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


November 27th, 2012

Some Occupational Exposures May Increase the Risk of Breast Cancer

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Some jobs that expose workers to potential hormone-disrupting chemicals have been associated with a 42 percent increased risk of developing breast cancer, according to the results of a study published in Environmental Health.[1] A 2009 scientific statement from the Endocrine Society identified a variety of endocrine-disrupting chemicals that affect male and female reproduction, breast development and […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


October 1st, 2012

Screening Radiation Exposure May Increase Breast Cancer Risk in Some BRCA Mutation Carriers

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Radiation exposure from x-rays, mammograms, and other diagnostic tests prior to age 30 may increase the risk of breast cancer in women who carry BRCA1 or BRCA2 mutations, according to the results of a large, retrospective cohort study published in the British Medical Journal. Inherited mutations in two genes—BRCA1 and BRCA2—have been found to greatly […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


August 28th, 2012

Genetic Testing Appropriate for Some Women with Triple-Negative Breast Cancer

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A study conducted in Greece found elevated rates of BRCA1 gene mutations in women with triple-negative breast cancer, particularly those who had been diagnosed with cancer at a young age. These results were published in Breast Cancer Research and Treatment. Inherited mutations in two genes—BRCA1 and BRCA2—have been found to greatly increase the lifetime risk of […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer, Triple Negative Breast Cancer


July 24th, 2012

Post Oophorectomy Estrogen May Be Safe for Younger, Not Older, Women

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Women under 40 who use estrogen to manage menopausal symptoms after having their ovaries removed do not have an increased risk of breast cancer, but their older counterparts might, according to the results of a study published in Obstetrics and Gynecology. Women who carry an inherited mutation in one of two genes—BRCA1 and BRCA2—have a substantially […]

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Tags: Breast Cancer, General, HBOC, News, Other News Topics (not Types of Cancer), Screening/Prevention Breast Cancer


June 14th, 2012

Radiation to Chest for Childhood Cancer Increases Breast Cancer Risk

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Radiation therapy to the chest for the treatment of childhood cancer increases a girl’s risk of developing breast cancer at a young age, even if fairly low doses of radiation are given. These results were presented at the 2012 Annual Meeting of the American Society of Clinical Oncology. Radiation therapy is an important component of […]

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Tags: Breast Cancer, HBOC, Health and Wellness, News, Screening/Prevention Breast Cancer


February 17th, 2012

Lynch Syndrome Also Linked with Breast and Pancreatic Cancer

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A study of families with Lynch Syndrome has expanded the list of cancers related to the condition: carriers of a Lynch Syndrome gene mutation also appear to have an increased risk of breast cancer and pancreatic cancer. These results were published in the Journal of Clinical Oncology. Lynch Syndrome, also known as hereditary nonpolyposis colorectal […]

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Tags: Bladder Cancer, Breast Cancer, Colon Cancer, Gastric Cancer, General Renal Cancer, General Retinoblastoma, HBOC, News, Ovarian Cancer, Pancreatic Cancer, Rectal Cancer, Renal Cancer


November 8th, 2011

A BRCA Gene Mutation in the Family Does Not Increase Cancer Risk for Those Without the Mutation

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For women who do not have a BRCA1 or BRCA2 gene mutation, having a close relative with one of these mutations does not increase breast cancer risk. These results were published in the Journal of Clinical Oncology. Inherited mutations in two genes—BRCA1 and BRCA2—have been found to greatly increase the lifetime risk of developing breast […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


September 15th, 2011

BRCA-Related Cancers Diagnosed at Younger Age in Subsequent Generations

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In a study that evaluated two generations of women with BRCA1 or BRCA2 mutations, breast and ovarian cancers tended to be diagnosed at a younger age in the later generation. These results were published in Cancer. Inherited mutations in two genes—BRCA1 and BRCA2—have been found to greatly increase the lifetime risk of developing breast and […]

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Tags: Breast Cancer, HBOC, News, Ovarian Cancer, Screening/Prevention Breast Cancer, Screening/Prevention Ovarian Cancer


September 2nd, 2011

CHEK2 Gene Mutations Increase Breast Cancer Risk

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Mutations in the CHEK2 gene increase the risk of breast cancer, particularly among women who also have a family history of the disease. These results were published in the Journal of Clinical Oncology. Mutations in the BRCA1 and BRCA2 genes are known to greatly increase a woman’s lifetime risk of breast and ovarian cancer, but […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer


August 2nd, 2011

Genetic Testing Recommendations by Physicians Don’t Always Follow Guidelines

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According to a survey of more than 1,800 US physicians, decisions about who should be referred for BRCA1/2 testing are not always consistent with guidelines. These results were published in Cancer. Inherited mutations in two genes—BRCA1 and BRCA2—have been found to greatly increase the lifetime risk of developing breast and ovarian cancer. Mutations in these […]

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Tags: Breast Cancer, HBOC, News, Ovarian Cancer, Screening/Prevention Breast Cancer, Screening/Prevention Ovarian Cancer


July 12th, 2011

More Personalized Breast Cancer Screening May Provide Benefits

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Rather than applying a single set of breast cancer screening guidelines to most women, a more individualized approach that considers risk factors such as breast density may help to balance the benefits and costs of screening. These results were published in the Annals of Internal Medicine. A mammogram is an X-ray of the breast. A […]

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Tags: Breast Cancer, HBOC, News, Screening/Prevention Breast Cancer