Items Tagged ‘PV’

October 10th, 2016

Myeloproliferative Neoplasms Greatly Affect Patient Quality of Life

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According to results from the myeloproliferative neoplasms (MPN) Landmark survey, MPN’s negatively affect the quality of life and overall health of patients even a year before their diagnosis. Myeloproliferative neoplasms (MPN) are a related group of blood cancers. In these disorders, the bone marrow cells that produce blood cells develop and function abnormally. The three […]

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Tags: essential thrombocythemia, ET, mpn, Myeloproliferative Neoplasms MPN, News, PMF, polycythemia vera, primary myelofibrosis, PV


June 21st, 2016

Jakafi Superior to Standard Treatment in Polycythemia Vera

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Treatment with Jakafi® (ruxolitinib) was superior to best available treatment among patients with inadequately controlled polycythemia vera (PV). These results were recently presented at the 21st Congress of the European Hematology Association (EHA) in Copenhagen, Denmark. PV is a type of myeloproliferative neoplasm (MPN) in which the body produces a larger than normal amount of […]

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Tags: jakafi, mpn, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV, ruxolitinib


December 29th, 2015

All Symptomatic Polycythemia Vera Patients May Benefit From Treatment with a JAK2 Inhibitor

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Patients with polycythemia vera (PV) experience significant symptoms characterized by fatigue, itching, night sweats, bone pain, fever, and undesired weight loss that contribute to a poor quality of life which is often under appreciated by family and providers. Until recently, PV patients’ only treatment options were phlebotomy and hydroxyurea (HU). However, the development and approval […]

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Tags: jakafi, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV, ruxolitinib, treatment


July 7th, 2015

Jakafi® Appears Safe and Effective in Long-Term Disease Control in Polycythemia Vera

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In patients with polycythemia vera (PV), the drug Jakafi® (ruxolitinib) can help control disease at least one year. These findings were presented at the 20th Congress of the European Hematology Association in Vienna, Austria, June 11–14, 2015.[1] Polycythemia vera is a slow-growing type of blood cancer that belongs to a group of blood disorders called […]

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Tags: blood cancer, clinical trials, hydrea, jakafi, MPNs, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV, ruxolitinib


February 17th, 2015

Phase III Trial Finds Jakafi Superior to Standard Therapy for Polycythemia Vera

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A Phase III trial finds that Jakafi® (ruxolitinib) is more effective than standard therapy for patients with polycythemia vera (PV). These findings were published in the New England Journal of Medicine. Polycythemia vera is a slow-growing type of blood cancer that belongs to a group of blood disorders called myeloproliferative neoplasms (MPN). In these disorders, […]

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Tags: hydrea, hydroxyurea, jak1, JAK2, jakafi, mpn, Myeloproliferative Neoplasms MPN, myeloproliferative neoplastms, News, polycythemia vera, PV, PV treatment


January 22nd, 2015

Myeloproliferative Neoplasms: Making Progress in Polycythemia Vera and Myelofibrosis

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Myeloproliferative neoplasms (MPN) are a related group of blood cancers. In these disorders, the bone marrow cells that produce blood cells develop and function abnormally. The three main types of MPN are polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). In addition to developing on its own, myelofibrosis may also develop as a […]

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Tags: jakafi, mpn, myelofibrosis, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV


December 16th, 2014

Jakafi® Helps Maintain Blood Cells Levels in Polycythemia Vera

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CancerConnect News: A new drug called Jakafi® (ruxolitinib) appears to help patients with polycythemia vera (PV) maintain hematocrit control more effectively than best available therapy. These findings were presented at the 56th American Hematology Society Annual Meeting and Exposition, December 6–9, 2014, in San Francisco, California.[1] Polycythemia vera is a slow-growing type of blood cancer […]

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Tags: jakafi, mpn, myeloproliferative neoplasms, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV, ruxolitinib


December 15th, 2014

Switching from Best Available Therapy to Jakafi® Improves Outcomes in Polycythemia Vera

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Patients with polycythemia vera (PV) who begin treatment with best available therapy and then switch to treatment with Jakafi® (ruxolitinib) experience improved outcomes. These findings were presented at the 56th American Hematological Society Annual Meeting and Exposition, December 6–9, 2014, in San Francisco, California. Polycythemia vera is a slow-growing type of blood cancer that belongs […]

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Tags: jakafi, mpn, myeloproliferative neoplasms, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV


December 5th, 2014

Jakafi: First Drug Approved for Treatment of Polycythemia Vera

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The U.S. Food and Drug Administration today approved a new use for Jakafi (ruxolitinib) to treat patients with polycythemia vera, a chronic type of bone marrow disease. Jakafi is the first drug approved by the FDA for this condition. Polycythemia vera occurs when too many red blood cells are made in the bone marrow. Patients […]

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Tags: jakafi, mpn, Myeloproliferative Neoplasms MPN, News, PV


August 6th, 2014

FDA Accepts Supplemental New Drug Application for Jakafi and Priority Review Granted for the Treatment of Polycythemia Vera

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The  U.S. Food and Drug Administration (FDA) has accepted for filing the supplemental New Drug Application (sNDA) for Jakafi® (ruxolitinib) as a potential treatment of patients with polycythemia vera (PV) who have had an inadequate response to or are intolerant of hydroxyurea. PV is a myeloproliferative neoplasm (MPN) characterized by an overproduction of normal red […]

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Tags: Info Type, jakafi, mpn, Myeloproliferative Neoplasms MPN, News, polycythemia vera, PV, ruxolitinib