Items Tagged ‘Stage I Node Negative Breast Cancer’

September 7th, 2016

MammaPrint Might Help Identify Breast Cancer Patients Who Could Safely Opt Out of Chemo

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MammaPrint, a 70-gene signature test, might help healthcare providers and patients determine whether they will derive a benefit from chemotherapy, or if they could safely choose to not receive chemotherapy for early-stage breast cancer. These results need to be validated, and compared to other tests in order to confirm findings and determine true clinical utility […]

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Tags: Breast Cancer, early-stage, hereditary, MammaPrint, News, Stage I Node Negative Breast Cancer


July 27th, 2016

Neratinib Improves Cancer-Free Survival in Early Breast Cancer

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The targeted agent neratinib (PB272), which is still in clinical trials, demonstrated an improvement in cancer-free survival when used after Herceptin® (trastuzumab) in early-stage, HER2-positive breast cancer. Approximately 20-30% of breast cancer is referred to as human epidermal growth factor receptor-2 (HER2)-positive.  This means that the breast cancer cells have too many HER2 proteins on […]

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Tags: Breast Cancer, early breast cancer, exteNET, HER2-positive, herceptin, neratinib, News, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, trastuzumab. her2


June 7th, 2016

Treatment with Aromatase Inhibitors for 10 Years Improves Cancer-Free Survival in Breast Cancer

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Among postmenopausal women with hormone-positive, early breast cancer, treatment with aromatase inhibitors (AIs) for 10 years significantly improves cancer-free survival, compared to the 5-year standard length of AI treatment.  However, quality of life issues, bone density concerns, and a patient’s risk of a recurrence should be taken into consideration to determine the optimal length of […]

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Tags: AIs, aromatase inhibitors, Breast Cancer, early-stage, hormone-positive, HR+, News, postmenopausal, Stage I Node Negative Breast Cancer, survival


April 28th, 2016

Some Premenopausal Women Benefit from Exemestane Compared to Tamoxifen

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Among premenopausal women with hormone-positive, early breast cancer who are considered to have a high risk of a cancer recurrence, the use of Aromasin® (exemestane) versus tamoxifen improves cancer-free survival at 5 years. These results were recently published in the Journal of Clinical Oncology. The majority of breast cancers, referred to as hormone-positive breast cancers, […]

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Tags: aromasin, Breast Cancer, exemestane, HER2-negative, hormone-positive, News, premenopausal, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, tamoxifen


March 28th, 2016

Dose-Dense Chemotherapy for Premenopausal Breast Cancer Improves Survival

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Premenopausal women who have been diagnosed with breast cancer have improved survival if their chemotherapy doses are delivered every two weeks, compared to every three weeks. These results were recently presented at the 2016 European Breast Cancer Conference (EBCC-10) in the Netherlands. Chemotherapy following surgery is a standard treatment option for premenopausal women diagnosed with […]

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Tags: Breast Cancer, clinical trials, dose-dense, Metastatic Breast Cancer, News, premenopausal, research, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer


January 25th, 2016

ASCO Publishes Breast Cancer Survivorship Guidelines

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The American Society of Clinical Oncology (ASCO), in collaboration with the American Cancer Society (ACS), have released updated guidelines regarding follow-up care for breast cancer survivors. The updated guidelines were recently published in the Journal of Clinical Oncology. There is an estimated 3.1 million breast cancer survivors alive today in the United States. At present, […]

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Tags: ACS, American cancer society, American Society of Clinical Oncology, Breast Cancer, Carcinoma In Situ Breast cancer, follow-up, guidelines, Inflammatory Breast Cancer, Metastatic Breast Cancer, News, Recurrent Breast Cancer, Screening/Prevention Breast Cancer


November 30th, 2015

Radiation After Lumpectomy Improves Outcomes Among Elderly with Triple-Negative Breast Cancer

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The addition of radiation therapy following a lumpectomy appears to significantly improve outcomes among elderly women with triple-negative breast cancer. These results were recently presented at the 2015 Breast Cancer Conference in San Francisco, CA. Approximately 10-20% of breast cancers are referred to as triple-negative breast cancer (TNBC). These types of cancers are both hormone-negative, […]

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Tags: Breast Cancer, lumpectomy, News, radiation, Stage I Node Negative Breast Cancer, THBC, Triple Negative Breast Cancer


October 8th, 2015

Low Oncotype® Recurrence Score® Identifies Group of Women with Early Stage Breast Cancer That can Avoid Chemotherapy

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The results of a study presented at the European Cancer Congress demonstrate that early-stage breast cancer patients with a low Oncotype DX® Recurrence Score® result of 10 or less who received hormonal therapy alone without chemotherapy had less than a one percent chance of distant recurrence at five years. The results are the first to be […]

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Tags: Breast Cancer, clinical trial, early-stage breast cancer, News, oncotype dx, Stage I Node Negative Breast Cancer, Tailorx, Trial Assigning Individualized Options for Treatment (Rx)


September 16th, 2015

A Vegan or Vegetarian Diet May Help Improve Treatment of Triple-Negative Breast Cancer

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Early research suggests that a vegan or vegetarian diet low in the amino acid methionine may help improve treatment of triple-negative breast cancers. These findings were reported in the journal Clinical Cancer Research. The majority of breast cancers are hormone receptor-positive, meaning that the cancer cells are stimulated to grow from exposure to the female […]

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Tags: Breast Cancer, diet, HER2-negative, News, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, TRAIL-R2, treatment, triple negative, vegan, vegetarian


September 8th, 2015

Biomarker May Help Improve Treatment of Triple-Negative Breast Cancer

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Researchers have found a biomarker that appears active in the growth and spread of triple-negative breast cancer. Known as interleukin-13 receptor alpha 2 (IL13Ralpha2), the biomarker may help doctors identify patients at high risk of disease spread and potentially provide a target for treatment. These findings were reported in Breast Cancer Research. The majority of […]

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Tags: biomarker, Breast Cancer, Carcinoma In Situ Breast cancer, HER2-negative, IL13Ralpha2, News, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, Triple Negative Breast Cancer


September 1st, 2015

Women with Early Breast Cancer Have Fewer Side Effects with Shorter Courses of Radiation

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Women with early breast cancer have fewer side effects when they’re treated with shorter courses of radiation at higher doses than with conventional radiation to the whole breast. These findings were reported in JAMA Oncology.[1] Treatment with shorter course of radiation at higher doses is known as hypofractionated radiation therapy. This approach allows for less […]

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Tags: Breast Cancer, Carcinoma In Situ Breast cancer, conventional radiation, DCIS, hypofractionated radiation therapy, News, radiation, Stage I, Stage I Node Negative Breast Cancer, Stage II, Stages II-III Breast Cancer


June 2nd, 2015

Combination of Iniparib, Gemzar®, and Carboplatin Active in Initial Treatment of Early-Stage Triple-Negative Breast Cancer

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The combination of iniparib, Gemzar® (gemcitabine), and carboplatin appears promising in the initial treatment of patients with early-stage triple-negative breast cancer with a BRCA1/2 mutation. In addition, researchers have found ways to identify patients without a BRCA mutation who are likely to benefit. These findings were published in the Journal of Clinical Oncology. Breast cancers […]

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Tags: BRCA1/2 mutation, Breast Cancer, carboplatin, early-stage, gemzar, Iniparib, News, Stage I Node Negative Breast Cancer, Triple Negative Breast Cancer


January 27th, 2015

Breast Cancer Research: Have We Made Progress?

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Published results from research studies in breast cancer in the last year represent several practice changing milestones. CancerConnect News coverage of advances in the management of breast cancer included the following key developments: 2014: Have we Made Progress? Recent Study Finds That African American Women Less Likely To Receive Standard Breast Cancer Treatment Breast Cancer […]

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Tags: Breast Cancer, breast cancer research, Carcinoma In Situ Breast cancer, Inflammatory Breast Cancer, Metastatic Breast Cancer, News, Recurrent Breast Cancer, Screening/Prevention Breast Cancer, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, Supportive Care Breast Cancer


December 19th, 2014

Study Confirms Role of Ovarian Suppression and Aromasin for Younger Women With Hormone-sensitive Breast Cancer

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Ovarian suppression combined with the anti-estrogen drug Aromasin® (exemestane) appears to greatly reduce the risk of breast cancer recurrence in younger women according to the results of the Suppression of Ovarian Function Trial (SOFT) presented at the 2014 San Antonio Breast Cancer Symposium in Texas.[1] These results were also published online simultaneously in The New […]

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Tags: aromasin, Breast Cancer, News, ovarian suppression, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, tamoxifen


December 18th, 2014

Breast Cancer Patients Are Now Living Longer without Relapse

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Survival without relapse for patients with early-stage breast cancer has improved significantly over the past 30 years, particularly among women with HER2-positive disease. These findings were recently published in the Journal of Clinical Oncology. Cancer is considered relapsed when disease returns after it has been in remission following treatment, meaning that signs and symptoms have disappeared. Preventing relapse—or […]

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Tags: Breast Cancer, cancer, HER2, News, recurrence, Recurrent Breast Cancer, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer