Items Tagged ‘Stem Cell Transplant’

October 12th, 2016

HOVON Trial: Autologous Stem Cell Transplant Remains Superior to Novel Agents for Treatment of Multiple Myeloma

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A large, comparative, phase III HOVON clinical trial recently confirmed that upfront autologous stem cell transplantation (ASCT) should still be the treatment of choice in younger patients with newly diagnosed multiple myeloma (MM). The findings of this trial clearly demonstrated that ASCT should remain the preferred treatment for younger patients with MM. The clinical trial […]

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Tags: ASCT, bortezomib, clinical trial, cyclophosphamide, dexamethasone, HOVON, Multiple Myeloma, News, Stem Cell Transplant, velcade


March 30th, 2016

Defitelio® Approved for Life-Threatening Complication of Stem Cell Transplant

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The United States Food and Drug Administration (FDA) has approved Defitelio® (defibrotide sodium) for the treatment of hepatic veno-occlusive disease (VOD) following a stem cell transplant. Defitelio is the first approved treatment for severe hepatic VOD. Hepatic VOD is a rare, but life-threatening complication that can occur following chemotherapy and a stem cell transplant (SCT) […]

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Tags: Chemotherapy, chemotherpay, hepatic VOC, Hodgkin's Lymphoma, HSCT, Leukemia, Lymphoma, Multiple Myeloma, News, Non-Hodgkin's Lymphoma, Stem Cell Transplant


December 30th, 2015

Myeloablative Treatment Regimens Superior to Reduced Intensity Treatment for AML and MDS Patients Undergoing Stem Cell Transplant

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Hematopoietic Stem Cell Transplant (SCT) is a standard and potentially curative treatment for individuals with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Historically only high dose myeloablative treatment regimens were utilized since they were thought necessary to eradicate the malignant cells in the bone marrow. In recent years, SCT physicians have increasingly used reduced […]

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Tags: Acute Myeloid Leukemia, Allogeneic Stem Cell Transplant, AML, General Myelodysplastic Syndrome, hematopoietic stem cell transplant, Leukemia, MDS, Myelodysplastic Syndrome, News, sct, Stem Cell Transplant


December 14th, 2015

Prospective Study Shows Age Doesn’t Affect Survival Outcomes in Patients with Myelodysplastic Syndrome (MDS) Who Receive a Hematopoietic Cell Transplant (HCT)

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Results from a prospective study of 1,280 patients with myelodysplastic syndrome (MDS) showed that survival at 100 days and at two years following hematopoietic cell transplant (HCT) for patients aged 65 and older is comparable to patients aged 55 to 64. The study demonstrates that age alone should not be a determinant when considering HCT […]

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Tags: HCT, hematopoietic cell transplant, MDS, Medicare, Myelodysplastic Syndrome, News, Stem Cell Transplant


November 12th, 2013

Treatment with Early Stem Cell Transplant Improves Outcomes in Aggressive NHL

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Early autologous stem cell transplantation resulted in improved progression-free survival in patients with high-intermediate risk or high-risk disease who experienced a response to induction therapy, according to the results of a study published in the <i>New England Journal of Medicine</i>. Non-Hodgkin’s lymphoma (NHL) is a form of cancer that begins in the cells of the […]

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Tags: Autologous Stem Cell Transplant, Highly Aggressive/High Grade Non-Hodgkin's Lymphoma, News, Non-Hodgkin's Lymphoma, Stem Cell Transplant


March 22nd, 2013

Zevalin Plus BEAM Chemotherapy Superior to BEAM Alone in Aggressive Lymphoma

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Standard-dose Zevalin® (ibritumomab tiuxetan) combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM therapy alone as a conditioning regimen for autologous stem cell transplantation (ASCT), according to the results of a study published in Cancer. High-dose chemotherapy plus autologous stem cell transplantation (ASCT) is standard therapy for refractory/relapsed aggressive lymphoma; however, […]

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Tags: Aggressive/Intermediate Grade Non-Hodgkin's Lymphoma, Autologous Stem Cell Transplant, Lymphoma, News, Non-Hodgkin's Lymphoma, Stem Cell Transplant


August 6th, 2012

Antiretroviral Drug May Prevent Graft-Versus-Host Disease

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The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according to the results of a study published in the New England Journal of Medicine. Stem cell transplantation (also called bone marrow transplantation) is a procedure often used to treat […]

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Tags: Allogeneic Stem Cell Transplant, News, Stem Cell Transplant


November 10th, 2011

Mini-Transplants Continue to Show Promise for Older Patients with AML

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Less toxic cancer treatment followed by an allogeneic stem cell transplant is showing promise for older patients with advanced blood and bone marrow cancers such as acute myeloid leukemia (AML). These results were published in the Journal of the American Medical Association. Acute myeloid leukemia is a cancer of the bone marrow and blood characterized […]

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Tags: Acute Myeloid Leukemia, Leukemia, News, Stem Cell Transplant


May 23rd, 2011

Many Patients with “Chemo Brain” Recover within Five Years

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A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients. For some patients, however, symptoms may persist for more than five years after treatment. These findings were recently reported in the Journal of Clinical Oncology. Chemo brain refers […]

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Tags: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Promyelocytic Leukemia, Adult Acute Lymphoblastic Leukemia, Advanced Stage Hodgkin's Lymphoma, Aggressive/Intermediate Grade Non-Hodgkin's Lymphoma, Allogeneic Stem Cell Transplant, Childhood Acute Lymphoblastic Leukemia, Chronic Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Early Stage Hodgkin's Lymphoma