Items Tagged ‘Triple Negative Breast Cancer’

June 30th, 2016

Tecentriq™ Plus Abraxane® Effective Combo in Difficult to Treat Breast Cancer

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The combination of the immune stimulating agent Tecentriq™ (atezolizumab), plus the chemotherapy agent Abraxane® (nab-paclitaxel) is effective in providing anti-cancer responses among patients with advanced triple-negative breast cancer (TNBC). These results were recently reported at the 2016 annual meeting of the American Society of Clinical Oncology (ASCO). Approximately 10-20% of breast cancers are referred to […]

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Tags: Breast Cancer, immunotherapy, Metastatic Breast Cancer, News, Recurrent Breast Cancer, Tecentriq, tnbc, Triple Negative Breast Cancer


May 30th, 2016

New Breakthrough May Advance Triple Negative Breast Cancer Treatment

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By Helen Young Scientists at The Scripps Research Institute have developed a new drug candidate that lowers the growth rate of tumor cells in animal models1 in one of the most difficult cancers to battle: triple negative breast cancer. This is the first time that scientists have been able to take a genetic sequence and design […]

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Tags: Breast Cancer, genetic sequence, microRNA, microRNA-96, News, RNA, Targaprimir-96, targeted therapy, Triple Negative Breast Cancer


March 24th, 2016

Complete Pathologic Responses Associated with Prognosis in Triple-Negative Breast Cancer

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A complete pathologic response (no cancer cells detected through microscopic evaluation) appears to be the most accurate indicator of long-term prognosis for women with triple-negative breast cancer. These results were recently presented at the 2015 annual meeting of the San Antonio Breast Cancer Symposium (SABCS). Approximately 10-20% of breast cancers are referred to as triple-negative […]

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Tags: Breast Cancer, complete pathologic response, HER2-negativeresearch, long-term prognosis, News, pCR, tnbc, Triple Negative Breast Cancer


January 7th, 2016

Atezolizumab Plus Abraxane Promising New Treatment for Triple-Negative Breast Cancer

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The investigative agent, atezolizumb, in addition to the chemotherapy agent, Abraxane (nab-paclitaxel), provides high anti-cancer responses among patients with triple-negative breast cancer. These results were recently presented at the 2015 annual San Antonio Breast Cancer Symposium. Approximately 10-20% of breast cancers are referred to as triple-negative breast cancer (TNBC). These types of cancers are both […]

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Tags: abraxane, atezolizumab, Breast Cancer, News, tnbc, Triple Negative Breast Cancer


December 23rd, 2015

Abraxane® Combo Promising in Triple Negative Breast Cancer

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The chemotherapy combination consisting of Abraxane® (nab-paclitaxel) plus carboplatinum (carbo) improves outcomes compared with Abraxane plus Gemzar (gemcitabine) for triple negative breast cancer. These results were presented at the 2015 annual San Antonio Breast Cancer Symposium (SABCS). Approximately 10-20% of breast cancers are referred to as triple negative breast cancer (TNBC). These types of cancers […]

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Tags: abraxane, Breast Cancer, gemzar, News, tnbc, Triple Negative Breast Cancer


December 22nd, 2015

Adding Carboplatin to Pre-surgery Chemotherapy Improves Survival for Patients with Triple-Negative Breast Cancer

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Adding carboplatin to pre-surgery chemotherapy improved disease-free survival for patients with triple-negative breast cancer (TNBC), according to results from a German clinical study released at the San Antonio Breast Cancer Symposia.1 Breast cancers that are not stimulated to grow from exposure to estrogen or progesterone and are HER2 (human epidermal growth factor receptor)-negative are called […]

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Tags: Breast Cancer, carboplatin, HER2-negative, News, surgery, tnbc, Triple Negative Breast Cancer


November 30th, 2015

Radiation After Lumpectomy Improves Outcomes Among Elderly with Triple-Negative Breast Cancer

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The addition of radiation therapy following a lumpectomy appears to significantly improve outcomes among elderly women with triple-negative breast cancer. These results were recently presented at the 2015 Breast Cancer Conference in San Francisco, CA. Approximately 10-20% of breast cancers are referred to as triple-negative breast cancer (TNBC). These types of cancers are both hormone-negative, […]

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Tags: Breast Cancer, lumpectomy, News, radiation, Stage I Node Negative Breast Cancer, THBC, Triple Negative Breast Cancer


September 8th, 2015

Biomarker May Help Improve Treatment of Triple-Negative Breast Cancer

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Researchers have found a biomarker that appears active in the growth and spread of triple-negative breast cancer. Known as interleukin-13 receptor alpha 2 (IL13Ralpha2), the biomarker may help doctors identify patients at high risk of disease spread and potentially provide a target for treatment. These findings were reported in Breast Cancer Research. The majority of […]

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Tags: biomarker, Breast Cancer, Carcinoma In Situ Breast cancer, HER2-negative, IL13Ralpha2, News, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, Triple Negative Breast Cancer


June 2nd, 2015

Combination of Iniparib, Gemzar®, and Carboplatin Active in Initial Treatment of Early-Stage Triple-Negative Breast Cancer

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The combination of iniparib, Gemzar® (gemcitabine), and carboplatin appears promising in the initial treatment of patients with early-stage triple-negative breast cancer with a BRCA1/2 mutation. In addition, researchers have found ways to identify patients without a BRCA mutation who are likely to benefit. These findings were published in the Journal of Clinical Oncology. Breast cancers […]

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Tags: BRCA1/2 mutation, Breast Cancer, carboplatin, early-stage, gemzar, Iniparib, News, Stage I Node Negative Breast Cancer, Triple Negative Breast Cancer


December 10th, 2014

Initial Results of PD-1 Checkpoint Inhibitors Evaluated in Triple-Negative Breast Cancer Presented in San Antonio

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The initial results from a phase 1 trial evaluating the checkpoint inhibitor Keytruda® (pembrolizumab) in patients with heavily pretreated triple-negative breast cancer were recently reported at the San Antonio Breast Cancer Symposium (SABCS). The cancer immunotherapy strategy known as programmed cell death 1 (PD-1) has generated great excitement for its ability to help the immune […]

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Tags: Breast Cancer, immunotherapy, keytruda, Metastatic Breast Cancer, News, PD-1, Recurrent Breast Cancer, tnbc, Triple Negative Breast Cancer


July 31st, 2012

Potential New Target Identified in Triple-Negative Breast Cancer

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A subset of triple-negative breast cancers contains a genetic change that contributes to cancer growth and may be possible to target with drugs. These results were published in Nature. Each year, more than 220,000 women are diagnosed with breast cancer in the United States. For these women, tests to identify certain characteristics of the tumor […]

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Tags: Metastatic Breast Cancer, News, Recurrent Breast Cancer, Stage I Node Negative Breast Cancer, Stages II-III Breast Cancer, Triple Negative Breast Cancer