Items Tagged ‘Uncategorized’

June 2nd, 2014

Ruxolitinib Plus Capecitabine Improves Survival in Metastatic Pancreatic Cancer Patients with Local and Systemic Inflammation

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In a study presented at the 2014 ASCO meeting and published in the Journal of Clinical Oncology, researchers reported that treatment with ruxolitinib plus capecitabine improved overall survival and progression-free survival in metastatic pancreatic cancer patients with local and systemic inflammation (INFL). INFL is a common marker of cancer that is associated with adverse prognoses in […]

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May 22nd, 2014

New biopsy method shows prostate cancers considered 'low risk' may be anything but

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More and more men who have low-risk prostate cancers are forgoing treatment and opting for active surveillance, in which their tumors are closely monitored with PSA tests, digital rectal exams and ultrasounds at regular intervals. Nearly 400 men are now enrolled in the UCLA active surveillance program, the largest in Southern California. However, according to […]

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May 22nd, 2014

Study Using Comprehensive Genomic Tumor Testing to Match Lung Cancer Patients with Targeted Therapies Transforms Care

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Data Supports Routine Tumor Genotyping for Patients with Advanced Lung Cancers; May Improve Survival New data from a study led by Memorial Sloan Kettering physicians that used targeted therapy for patients with the most common type of lung cancer has helped transform treatment for the disease. The Lung Cancer Mutation Consortium (LCMC), composed of a […]

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May 21st, 2014

CO-1686 Lung Cancer Treatment Receives Breakthrough Designation by FDA

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Lung cancer remains the leading cause of cancer-related deaths worldwide. In the United States, NSCLC accounts for 75–80% of all lung cancers. Although progress has been made in recent years the majority of patients with advanced stage lung cancer still die from their disease. New treatments are sorely needed.  Clovis Oncology Inc. recently reported that […]

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May 2nd, 2014

Preoperative Chemotherapy Improves Survival in NSCLC

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Pre-operative (neoadjuvant) chemotherapy for non-small cell lung cancer (NSCLC) is associated with a significant reduction in the risk of death, according to the results of a meta-analysis published in The Lancet. Lung cancer remains the leading cause of cancer-related deaths worldwide. In the United States, NSCLC accounts for 75–80% of all lung cancers. For patients with […]

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April 1st, 2014

Ceritinib Highly Active in Advanced ALK-Positive NSCLC

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The investigational compound ceritinib (LDK378) was highly active in patients with advanced ALK-positive non-small cell lung cancer, according to the results of a study published in the New England Journal of Medicine. Lung cancer is the leading cause of cancer death in the U.S. and around the world. Up to 7 percent of non-small cell lung […]

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March 6th, 2014

Nintedanib Plus Docetaxel is Effective Second-Line Therapy for NSCLC

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Nintedanib in combination with docetaxel is an effective second-line option for patients with advanced non-small cell lung cancer previously treated with one line of platinum-based therapy, according to the results of a study published in The Lancet Oncology. Lung cancer remains the leading cause of cancer death in the United States. Non-small cell lung cancer (NSCLC) […]

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February 19th, 2014

Stool Test Spots Most Colon Cancers

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A stool test known as the fecal immunochemical test (FIT) is accurate in diagnosing most colorectal cancers, according to a meta-analysis published in the Annals of Internal Medicine. Screening is crucial for the prevention and early detection of colorectal cancer. The American Cancer Society currently recommends that people at average risk of colorectal cancer begin […]

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February 7th, 2014

Genomic Health Announces Results of Oncotype DX(R) Colon Cancer Studies Presented at 2014 American Society of Clinical Oncology Gastrointestinal Cancer (ASCO GI) Symposium

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New data show real-life impact of Oncotype DX on treatment decisions, underscore clinical validity and utility of the test REDWOOD CITY, Calif., Jan. 29, 2014 /PRNewswire/ — Genomic Health, Inc. (Nasdaq: GHDX) today announced results from the Oncotype DX® colon cancer test studies that were recently presented at the 2014 American Society of Clinical Oncology […]

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June 24th, 2013

No Increased Risk of Oral HPV in Spouses of People with HPV-Positive Oropharyngeal Cancer

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Spouses of people who are diagnosed with human papillomavirus (HPV)-related oropharyngeal cancer have a risk of oral HPV that is similar to that of the general population. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). Oropharyngeal cancer is a type of head and neck cancer. The […]

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June 7th, 2012

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April 29th, 2011

Delay in Chemotherapy Increases Risk of Death in Colorectal Cancer

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When chemotherapy for colorectal cancer is delayed by more than four weeks following surgery, patients face an increased risk of death. These findings were recently reported at the American Society of Clinical Oncology’s annual Gastrointestinal Cancers Symposium. Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Stage III colorectal cancer […]

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January 11th, 2011

Study Evaluates Predictors of DCIS Outcomes

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Choice of treatment, choice of surgeon, and surgical margin (a measure of whether the cancer was completely removed) all appear to affect the risk of disease recurrence among women with ductal carcinoma in situ (DCIS) of the breast.  These findings were reported in the Journal of the National Cancer Institute. Ductal carcinoma in situ refers […]

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March 26th, 2010

Childhood Cancer Survivors Treated with Radiation Therapy at Increased Risk of Death from Heart Disease in Adulthood

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A dose of as little as 5 Gy of radiation therapy to the heart for the treatment of childhood cancers results in a significant increase in cardiac death later in life, according to a study recently published in the Journal of Clinical Oncology.[1] Survivors of childhood cancers are often at risk for long-term and late […]

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March 26th, 2010

Cost Versus Benefit Among Chemotherapy Drugs for Metastatic Colorectal Cancer

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New chemotherapy agents for metastatic colorectal cancer modestly improve survival time but come with substantial costs, according to the results of a study published in the Archives of Internal Medicine.[1] Metastatic colorectal cancer refers to cancer that has spread from the colon to distant sites in the body. Though metastatic colorectal cancer is considered incurable, […]

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