Latest Cancer News

Read the latest cancer news from the National Cancer Institute. The UNM Comprehensive Cancer Center is one of only 49 NCI-designated comprehensive cancer centers bringing leading, national cancer care to New Mexico.

Some Brain Cells May Help to Fuel Cancer Metastasis

Brain cells called astrocytes can activate PPAR-gamma, a growth protein in cancer cells that helps them gain a foothold in the brain, a new study shows. The findings suggest that drugs that block PPAR-gamma activity may help treat brain metastases.

Epigenetic Changes Pinpointed as the Cause of Some GISTs

Scientists may have pinpointed the cause of some gastrointestinal stromal tumors (GISTs), a rare cancer, according to a new NCI-funded study. However, the culprit isn’t a harmful genetic mutation, but another type of genetic change, what are called epigenetic alterations.

Targeted Drug Trio Improves Survival in Colorectal Cancer with BRAF Mutations

For people with colorectal cancer with a specific mutation in the BRAF gene, a treatment regimen of three targeted drugs can improve how long they live without increasing their risk of serious side effects, results from a new clinical trial show.

Prescribing Exercise as Cancer Treatment: A Conversation with Dr. Kathryn Schmitz

Updated guidelines on exercise in those living with cancer and cancer survivors were recently released. In this conversation, Dr. Kathryn Schmitz discusses what these new guidelines mean for doctors, patients, and survivors.

Home Is Where the Heart Is

Dr. Ned Sharpless discusses his return as NCI director after serving as acting commissioner of the Food and Drug Administration for 7 months.

Durvalumab Plus Chemotherapy Improves Survival in Small Cell Lung Cancer

A large clinical trial showed that adding the immunotherapy drug durvalumab (Imfinzi) to standard chemotherapy can prolong survival in some people with previously untreated advanced small cell lung cancer.

PARP Inhibitors Show Promise as Initial Treatment for Ovarian Cancer

In three large clinical trials of women with newly diagnosed ovarian cancer, treatment with a PARP inhibitor as first-line therapy, maintenance therapy, or both, extended the length of time before participants’ cancers came back or got worse.

Failed Alzheimer’s Drug Might Boost CAR T-Cell Therapy for Multiple Myeloma

Results from a new study suggest a potential way to improve the effectiveness of CAR T-cell therapy for multiple myeloma. The approach relies on a class of drugs called gamma-secretase inhibitors (GSIs), several of which have been studied to treat Alzheimer’s disease.

Analysis Shows Women with High Breast Cancer Recurrence Scores Benefit from Chemo

A TAILORx analysis shows women with early-stage breast cancer and high recurrence scores on the Oncotype DX who received chemotherapy with hormone therapy had better long-term outcomes than what would be expected from hormone therapy alone.

Dual-Function Virus Engineered to Kill Tumor Cells and Support Immune Cells

Researchers have engineered an oncolytic virus to kill cancer cells and boost the immune response against tumors. In a new study, the virus provided T cells around tumors with a hormone they need for their own cell-killing functions.