Cristian Bologa, PhD
Department of Internal Medicine,
Division of Translational Informatics
Cancer Therapeutics: Technology, Discovery and Targeted Delivery
I have been involved for the last 15 years in the data management and analytics, workflow processing, and in the decision making process for the discovery of new bioactive compounds in the Division of Biocomputing and Division of Translational Informatics at UNM. I have a broad background and more than 20 years of experience in protein and small molecule modeling, biomedical data science, chemoinformatics, and SAR for molecular discovery. I had significant contributions in developing and using new methods and tools for discovery of novel small bioactive molecules for integrins (LFA-1 and VLA-4), formyl peptide receptors (FPR-1 and FPRL1), for granularity induction in prostate cancer cell lines (LNCaP and PC3), for the anti-apoptotic member of the Bcl-2 family protein Bcl-B, and a very potent and selective agonist (G-1) for a membrane estrogen receptor (GPR30). In summary, I have a broad experience with developing and using innovative methods, tools, and platforms that support information intensive data discovery, and I am looking forward to working with the center members to support them with information intensive molecular discovery.