Items Tagged ‘CML’

September 19th, 2017

Pass it On: It’s Leukemia National Awareness Month

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Leukemia and lymphoma are both hematologic malignancies, meaning that they involve the blood or bone marrow. The American Cancer Society (ACS) estimates that there will be 60,140 new cases of leukemia and 24,400 deaths in 2016. For lymphoma, the ACS estimates that 81,080 new cases and 21,270 deaths will occur in the United States in […]

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Tags: all, AML, CLL, CML, Leukemia, News


June 14th, 2017

Sprycel Effective for Treatment of Pediatric Chronic Myeloid Leukemia

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In 2002, the FDA approved the drug Gleevec (imatinib) as a first-line therapy for adults with chronic myeloid leukemia (CML) caused by the fusion gene BCR-ABL, known as the Philadelphia chromosome. The approval dramatically extended the lives of patients with the condition and, in many ways, ushered in the era of molecularly-targeted treatments against cancer. […]

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Tags: BCR-ABL, Chronic Myeloid Leukemia, CML, dasatinib), Gleevec, imatinib, Leukemia, News, Philadelphia chromosome Sprycel


December 14th, 2016

FDA Grants Iclusig® Expanded Approval for CML

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The United States Food and Drug Administration (FDA) has granted Iclusig® (ponatinib) approval to treat all phases of chronic myeloid leukemia (CML) in adults, as well as Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ALL) who are not eligible for treatment with another tyrosine kinase inhibitor. The approval indication also includes adults with T3151-positive CML and T3151-positive […]

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Tags: Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, CML, Iclusig, Leukemia, News, PACE trial, Ph+ ALL, ponatinib, TKI, tyrosine kinase inhibitor


April 7th, 2015

Tasigna® Remains Superior to Gleevec® for Treatment of Newly Diagnosed Patients With Chronic Myeloid Leukemia

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Tasigna® (nilotinib) remains superior to Gleevec® (imatinib) for the treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia (PH+CML), according to the results of the six-year update from the ENESTnd trial which were presented at the 56th annual meeting of the American Society of Hematology (ASH) in San Francisco.  These data are consistent with that […]

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Tags: Chronic Myeloid Leukemia, CML, ENESTnd trial, Gleevec, imatinib, Leukemia, News, nilotinib, Philadelphia chromosome positive, Tasigna