Items Tagged ‘Colon Cancer’

April 25, 2018

Many Early Onset Colon Cancers are Caused by Genetic Mutations Passed Through Families

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CancerConnect News: One in every six colorectal cancer patients (16 percent) diagnosed under age 50 has at least one inherited genetic mutation that increases his or her cancer risk and many of these mutations could go undetected with the current screening approach, according to initial data from a statewide colorectal cancer screening study conducted at […]

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Tags: Colon Cancer, hereditary, lynch syndrome, News, ohio state-james cancer institute


April 10, 2018

Managing Side Effects From EGFR Inhibitors

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CancerConnect News: Epidermal Growth Factor Receptor (EGFR) inhibitor drugs are a type of precision cancer medicine commonly used to treat lung, colon, head and neck and other cancers that over express the EGFR.  There are several EGFR inhibitor drugs and these cause similar side effects. The EGFR pathway is a normal biologic pathway found in […]

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Tags: cetuximab, Colon Cancer, diarrhea, EGFR inhibitors, erbitux, erlotinib, gefitinib, Head and Neck Cancer, iressa, Lung Cancer, News, Panutumamab


February 21, 2018

Diagnosed with Colon Cancer: 10 Tips on How to Get The Most From Your Doctor

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1) Choose Your Doctor Carefully Medical oncologists are the primary doctors involved with colon cancer and work in collaboration with surgeons and gastroenterologists. Pick a medical oncologist carefully, rely on people you trust including nurses and other health care professionals who make help with recommendations.  Make sure your doctor is someone you feel comfortable interacting […]

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Tags: Colon Cancer, News


January 8, 2018

Ulixertinib A First-in-class ERK Inhibitor Shows Early Efficacy in Patients With Advanced Cancers

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CancerConnect News: The novel ERK1/2 kinase inhibitor ulixertinib displayed an acceptable safety profile and had clinical activity in patients whose cancers had mutations in the MAPK cell-signaling pathway, according to data from a recent phase 1 clinical trial.  Based on data from this trial, ulixertinib has received the U.S. Food and Drug Administration’s Fast Track […]

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Tags: Colon Cancer, ERK inhibitor, Lung Cancer, MAPK/ERK, Melanoma, News, Precision Cancer Medicine, targeted therapy, ulixertinib


January 5, 2018

Start 2018 Right: Plan for Cancer Screening and Save Lives!

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Screening guidelines should initiate conversations with your healthcare team.  Charles H Weaver MD, Editor CancerConnect CancerConnect News: The goal of cancer screening is to find disease at early stages in people who are otherwise asymptomatic—before it causes symptoms and when it may be more easily treatable.  Screening tests are not available for every type of […]

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Tags: breast, Breast Cancer, cancer screening, colon, Colon Cancer, lung, Lung Cancer, News, Skin Cancer


October 16, 2017

Targeting both BRAF and EGFR doubles progression-free survival in metastatic colorectal cancer

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Recent successes in genetically targeted precision cancer medicines are improving outcomes in a number of cancers.  Ensuring patients undergo genomic sequencing to determine if they have treatable targets is increasingly important to ensure patients receive the most appropriate personalized care. Precision cancer medicine utilizes molecular diagnostic testing, including DNA sequencing, to identify cancer-driving abnormalities in […]

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Tags: BRAF, Colon Cancer, erbitux, News, Precision Cancer Medicine, Rectal Cancer, V600E, vemurafenib, zelboraf


September 18, 2017

NSAIDs Decrease Risk of Colorectal Cancer

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Nonsteroidal anti-inflammatory drugs (NSAIDS) are medicines that are used for the treatment of a wide range of musculoskeletal illnesses including spinal disorders, osteoarthritis and inflammatory conditions like rheumatoid arthritis. NSAIDs effectively relieve pain, inflammation, and fever.  A number of treatment guidelines for osteoarthritis, rheumatoid arthritis, and chronic low back pain recommend the use of NSAIDs […]

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Tags: Colon Cancer, News, Rectal Cancer


June 21, 2013

Fitness in Middle Age Reduces Cancer Risk in Men

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In a large, long-term study, men with good cardiovascular fitness in middle age were less likely to develop and die from colorectal and lung cancers. These results were presented at 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO). Regular physical activity is known to have a broad range of health benefits, including […]

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Tags: Colon Cancer, Lung Cancer


June 20, 2013

Erbitux Plus FOLFIRI Outperforms Avastin Plus FOLFIRI for First-Line Treatment of Metastatic Colorectal Cancer

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For the initial (first-line) treatment of metastatic colorectal cancer with no KRAS gene mutations, the combination of Erbitux® (cetuximab) and FOLFIRI chemotherapy was more effective than the combination of Avastin® (bevacizumab) and FOLFIRI. These results were presented at the 2013 Annual Meeting of the American Society of Clinical Oncology. Erbitux and Avastin are both targeted therapies that […]

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Tags: Colon Cancer, Stage IV (D)/Relapsed Colon Cancer


April 29, 2011

Delay in Chemotherapy Increases Risk of Death in Colorectal Cancer

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When chemotherapy for colorectal cancer is delayed by more than four weeks following surgery, patients face an increased risk of death. These findings were recently reported at the American Society of Clinical Oncology’s annual Gastrointestinal Cancers Symposium. Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Stage III colorectal cancer […]

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Tags: Adjuvant (I-III, A-C) Colon Cancer, Colon Cancer, Rectal Cancer, Stages I-III Rectal Cancer


March 23, 2009

In Their Own Words: Colorectal Cancer Survivors

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Rozanne Prisament, Diagnosed at Age 50 I had absolutely no risk factors for colorectal cancer and had a healthy lifestyle, eating right, exercising, and getting at least eight hours of sleep. Although I rarely went to a doctor, preferring alternative remedies, I went to a general practitioner when the abdominal pain began. To my dismay […]

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Tags: Colon Cancer


March 13, 2009

Colon Cancer Overview

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Overview The colon and rectum are parts of the body’s digestive system and together form a long, muscular tube called the large intestine. The colon is the first 6 feet of the large intestine and the rectum is the last 8-10 inches. Treatment approaches differ between cancers of the colon or rectum and are, therefore, […]

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Tags: Colon Cancer


February 6, 2009

What Every Woman Should Know About Cancer Screening

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By Jennifer Maxon, RN Over the past several decades, long-term cancer survival rates have been on the rise.1 These improved outcomes are largely credited to screening measures for certain types of cancers. In general, cancer that can be detected and treated in its earliest stages, prior to any spread—and often prior to any symptoms—is associated […]

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Tags: Breast Cancer, Cervical Cancer, Colon Cancer, Melanoma, Skin Cancer


February 5, 2009

Advancements in Screening for Colorectal Cancer

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Although there is no doubt that screening for colorectal cancer saves lives, only about half of all Americans undergo the recommended screening for the disease. This low compliance rate to screening is perhaps the single greatest reason why colorectal cancer remains the second-leading cause of cancer-related deaths in the United States. This is despite the […]

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Tags: Colon Cancer


February 5, 2009

Understanding Targeted Therapy for Colorectal Cancer

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Targeted therapies are anticancer drugs that are designed to treat cancer cells while minimizing damage to normal, healthy cells. These drugs, which may be used in the treatment of colorectal cancer, interfere with specific pathways involved in cancer cell growth or survival. Some targeted therapies block growth signals from reaching cancer cells; others reduce the […]

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Tags: Colon Cancer