Items Tagged ‘olaparib’

October 10th, 2017

LynparzaTM Slows Spread of Inherited Breast Cancer Caused By BRCA Mutations

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LynparzaTM (olaparib), a new drug treatment for women with advanced ovarian cancer associated with defective BRCA genes also appears to slowe the progression of breast cancer caused in part by mutations in the BRCA gene.  BRCA is an inherited condition that causes up to 3% of all breast cancers. BRCA + breast cancer is particularly […]

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Tags: BRCA breast cancer, Breast Cancer, lynparza, News, olaparib, PARP inhibitor, Precision Cancer Medicine


July 12th, 2017

Is Lynparza a Precision Cancer Medicine for Prostate Cancer?

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Scientists have developed a new three-in-one blood test that has the potential to turn Lynparza (olaparib) into a precision medicine for prostate cancer. Lynparza is a PARP inhibitor, a newer precision cancer medicine that blocks enzymes involved in repairing damaged DNA, thereby helping to kill cancer cells. Lynparza became the first PARP inhibitor medicine to […]

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Tags: lynparza, News, olaparib, PARP inhibitor, Precision Cancer Medicine, Prostate Cancer


October 31st, 2016

Update on PARP Inhibitors for Ovarian Cancer with BRCA Mutations

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Each year in the United States, roughly 22,000 women are diagnosed with ovarian cancer and more than 15,000 die of the disease. Treatment for ovarian cancer commonly involves surgery and/or chemotherapy. Researchers continue to study new approaches for improving the outcomes of all women affected by ovarian cancer but progress has been slow. The PARP […]

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Tags: BRCA1, BRCA2, lynparza, News, niraparib, olaparib, Ovarian Cancer, PARP inhibitor, Recurrent Ovarian Cancer, Rucaparib, Stage I Ovarian Cancer, Stage II-IV Ovarian Cancer


October 29th, 2015

Gene-Targeted Drug Can Treat Prostate Cancer

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According to an international consortium of researchers led by experts at The Institute of Cancer Research, London, and The Royal Marsden, a pioneering drug developed to treat women with inherited cancers can also benefit men with advanced prostate cancer. Olaparib, the world’s first drug to reach the market targeted against inherited cancer mutations, was found […]

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Tags: advanced, DNA repair mutations, genomic testing, Locally Advanced Stage III (C) Prostate Cancer, Metastatic Stage IV (D) Prostate Cancer, News, olaparib, Prostate Cancer, treatment-resistant


September 9th, 2015

Lynparza Improves Overall Survival in High-Risk Gastric Cancer

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The combination of LynparzaTM (olaparib), and paclitaxel improves overall survival relative to paclitaxel alone in patients with metastatic gastric cancer and low or undetectable levels of a DNA damage response gene known as ATM. Gastric cancer refers to cancer of the stomach. The American Cancer Society estimates that 24,590 Americans will be diagnosed with gastric […]

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Tags: ATM, Gastric Cancer, lynparza, metastatic, News, olaparib, paclitaxel, PARP inhibitor, Stages III-IV Gastric Cancer


December 29th, 2014

Lynparza Approved in Advanced Ovarian Cancer

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CancerConnect News: The U.S. Food and Drug Administration has granted accelerated approval to LynparzaTM (olaparib), a new drug treatment for women with advanced ovarian cancer associated with defective BRCA genes. According to statistics from the American Cancer Society (ACS), ovarian cancer causes more deaths than any other cancer of the female reproductive system. The ACS […]

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Tags: brca, lynparza, News, olaparib, Ovarian Cancer, parp, Recurrent Ovarian Cancer, Stage II-IV Ovarian Cancer


October 21st, 2014

Adding Cediranib to Olaparib Markedly Improves Progression-Free Survival but Increases Toxicity in Recurrent Platinum-Sensitive Ovarian Cancer

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The addition of the antiangiogenic agent cediranib to the PARP inhibitor olaparib in women with recurrent platinum-sensitive ovarian cancer improves time to cancer progression and survival. The results of this study were recently reported in The Lancet Oncology. Each year in the United States, roughly 22,000 women are diagnosed with ovarian cancer and more than […]

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Tags: cedirnaib, News, olaparib, Ovarian Cancer, Recurrent Ovarian Cancer, Stage II-IV Ovarian Cancer