Items Tagged ‘Precision Cancer Medicine’

August 8th, 2017

Roadmap to Personalized Therapies for Sarcoma and other Aggressive Cancers

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Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages. Its aggressiveness, rarity and diversity continue to hinder efforts to identify effective therapies for people with this malignancy. Patient-derived orthotopic xenografts (PDOX) are unique models where a patient’s individual tumor is grown in […]

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Tags: News, Precision Cancer Medicine, Sarcoma


August 2nd, 2017

Pediatric MATCH Trial to Test Targeted Drugs in Childhood Cancers

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Today investigators at the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) announced the opening of enrollment for a unique precision medicine clinical trial. NCI-COG Pediatric Molecular Analysis for Therapy Choice (Pediatric MATCH) is a nationwide trial to explore whether targeted therapies can be effective for children and adolescents with solid tumors that […]

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Tags: Brain Cancer, brain tumors, children with solid tumors, histiocytoses, News, non-Hodgkin lymphomas, Non-Hodgkin's Lymphoma, Pediatric MATCH trial, Precision Cancer Medicine, targeted therapy


July 19th, 2017

New Study Suggests Most Cancers are Unavoidable Irrespective of Life Style

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Two thirds of cancers are unavoidable even if you live a healthy life, according to a study published by doctors from John Hopkins.  The research, published in the journal Science, indicates that the majority of cancer-causing mutations are due to DNA copying errors. The recent discovery challenges the widespread belief that cancer mutations are generally inherited or triggered […]

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Tags: All Cancer Types, General, genetic risk of cancer, News, Other News Topics (not Types of Cancer), Precision Cancer Medicine


July 18th, 2017

Opdivo Proves Superior to Yervoy for Adjuvant Treatment of Stage III-IV Melanoma

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A clinical trial evaluating Opdivo  (nivolumab) versus Yervoy (ipilimumab) in patients with stage IIIb/c or stage IV melanoma who are at high risk of recurrence following complete surgical resection has demonstrated a superior recurrence-free survival in patients receiving Opdivo compared to Yervoy. There remains an unmet need for additional treatment options for individuals with stage III and resected stage IV high-risk melanoma […]

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Tags: adjuvant therapy, checkmate-238, checkpoint inhibitor, Melanoma, News, nivolumab, opdivo, PD-1, Precision Cancer Medicine


July 12th, 2017

Is Lynparza a Precision Cancer Medicine for Prostate Cancer?

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Scientists have developed a new three-in-one blood test that has the potential to turn Lynparza (olaparib) into a precision medicine for prostate cancer. Lynparza is a PARP inhibitor, a newer precision cancer medicine that blocks enzymes involved in repairing damaged DNA, thereby helping to kill cancer cells. Lynparza became the first PARP inhibitor medicine to […]

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Tags: lynparza, News, olaparib, PARP inhibitor, Precision Cancer Medicine, Prostate Cancer


July 6th, 2017

First-Line Immunotherapy Treatment Can Improve Survival for Subset of Lung Cancer Patients

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Findings from a phase III clinical trial for advanced lung cancer patients could help oncologists better predict which patients are likely to receive the most benefit from immunotherapy as a first-line treatment based on the unique molecular characteristics of their tumor, according to a new study reported by a global team led by David Carbone, […]

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Tags: checkpoint inhibitors, immunotherapy, keytruda, Lung Cancer, News, nivolumab, nsclc, opdivo, Precision Cancer Medicine


July 5th, 2017

Genmab Announces Preliminary Cervical Cancer Data from Tisotumab Vedotin Phase I/II Study

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Data from an ongoing clinical study of tisotumab vedotin in solid tumors has demonstrated activity in the treatment of cervical cancer; 11 of 34 evaluable patients achieved a response; with a median time of treatment of 4.9 months and 7 responders are still ongoing or in follow up for progression. The GEN701 study is ongoing […]

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Tags: Cervical Cancer, MoAb, News, Precision Cancer Medicine, targeted therapy, Tisotumab Vedotin


May 18th, 2017

Opdivo Precision Cancer Medicine Improves Outcomes in Advanced Liver Cancer

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Results from the CheckMate 040 clinical trial have been recently reported and found that Opdivo (nivolumab), an immuno-oncology drug which acts by modulating the immune system, produces durable responses with long-term survival rates in patients with liver cancer, regardless of whether or not patients were infected with Hepatitis B or C.  These study results were […]

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Tags: CheckMate 040 nivolumab, immuno-oncology, Liver Cancer, News, opdivo, PD-1, Precision Cancer Medicine