Items Tagged ‘Sarcoma’

August 8th, 2017

Roadmap to Personalized Therapies for Sarcoma and other Aggressive Cancers

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Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages. Its aggressiveness, rarity and diversity continue to hinder efforts to identify effective therapies for people with this malignancy. Patient-derived orthotopic xenografts (PDOX) are unique models where a patient’s individual tumor is grown in […]

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Tags: News, Precision Cancer Medicine, Sarcoma


March 23rd, 2017

SWOG Launches National Immunotherapy Clinical Trial for Rare Cancers

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People with rare cancers now have the option of joining a national clinical trial testing leading-edge immunotherapies for a wide variety of tumor types. It’s the first federally funded immunotherapy trial devoted to rare cancers. Despite their name, rare cancers make up more than 20 percent of cancers diagnosed worldwide. The trial is called DART, […]

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Tags: All Cancer Types, General, immunotherapy, keytruda, Neuroblastoma, News, Other News Topics (not Types of Cancer), Retinoblastoma, Sarcoma, Vaginal Cancer


March 16th, 2017

Regional Chemotherapy Technique for Extremity Sarcoma Salvages Patients’ Limbs from Amputation

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Patients with a type of advanced malignant cancer of the arms or legs have typically faced amputation of the afflicted limb as the only treatment option.  However, a technique that limits the application of chemotherapy to the cancerous region can preserve limbs in a high percentage of these patients, researchers from five cancer centers in […]

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Tags: limb perfusion, News, Sarcoma


November 7th, 2016

Chemotherapy Before Surgery Improves Treatment of Sarcoma

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For patients with localized soft-tissue sarcoma of the trunk or extremities who are high risk for relapse, the use of anthracycline plus ifosfamide chemotherapy prior to surgery appears to improve survival. Chemotherapy administered before surgery is called neoadjuvant therapy and has not previously been demonstrated to improve outcomes in soft tissue sarcoma (STS). Soft tissue […]

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Tags: anthracycline, dacarbazine, epirubicin, for undifferentiated pleomorphic sarcoma, gemcitabine, ifosfamide, leiomyosarcoma, malignant peripheral nerve sheath tumors, neoadjuvant therapy, News, Sarcoma, soft tissue sarcoma


February 4th, 2016

Halaven Approved for Liposarcoma

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The United States Food and Drug Administration (FDA) has approved the chemotherapy agent Halaven (eribulin) for the treatment of liposarcoma. It’s the first drug approved for liposarcoma that has demonstrated an improvement in overall survival. Halaven is already approved for the treatment of advanced breast cancer. The approval indication for Halaven in the treatment of […]

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Tags: eribulin, fda, Halaven, liposarcoma, News, Sarcoma, soft tissue sarcoma, Soft Tissue Sarcomas, STS


November 2nd, 2015

Yondelis® Approved for Treatment of Soft Tissue Sarcoma

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The United States Food and Drug Administration (FDA) approved the chemotherapy agent, Yondelis® (trabectedin), for the treatment of liposarcoma and leiomyosarcoma—two types of soft-tissue sarcomas.1 The approval of Yondelis is for patients whose cancer is not able to be removed by surgery and/or has spread to distant sites in the body. This treatment is approved […]

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Tags: advanced, leimyosarcoma, liposarcoma, News, Sarcoma, Soft Tissue Sarcomas, trabectedin, yondelis


October 20th, 2015

Yondelis® Bests Standard Therapy in Liposarcoma and Leiomyosarcoma

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The chemotherapy agent, Yondelis® (trabectedine), improves outcomes compared to the standard agent, DTIC (dacarbazine), in patients with advanced liposarcoma or leiomyosarcoma that has recurred or progressed following prior therapies. These results were recently published as a “rapid communication” in the Journal of Clinical Oncology. Liposarcoma and leiomyosarcoma are both types of soft-tissue sarcomas.  Soft tissue […]

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Tags: dacarbazine, DTIC, leiomyosarcoma, liposarcoma, News, Sarcoma, Soft Tissue Sarcomas, trabectedine, yondelis


June 11th, 2015

Longer Overall Survival for Patients with Soft Tissue Sarcoma Treated with Halaven®

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Halaven® (eribulin) may extend overall survival in patients with previously treated, advanced soft tissue sarcoma (STS). These findings were presented at 2015 Annual Meeting of the American Society of Clinical Oncology (May 29–June 2, Chicago, Illinois) and published in the Journal of Clinical Oncology.[1] Soft tissue sarcomas are cancers that affect the connective and supportive […]

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Tags: ADI, adipocytic sarcoma, Halaven, leiomyosarcoma, LMS, News, Sarcoma, soft tissue sarcoma, Soft Tissue Sarcomas, STS


February 4th, 2015

YONDELIS® (trabectedin) for the Treatment of Patients with Advanced Soft Tissue Sarcoma

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The U.S. Food and Drug Administration (FDA) has granted Priority Review for the New Drug Application (NDA) for YONDELIS® (trabectedin) to treat patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes. YONDELIS® is a novel, multimodal, synthetically produced antitumor agent, originally derived from the sea squirt, Ecteinascidia turbinata. The anti-cancer medicine works […]

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Tags: General Sarcoma, News, Sarcoma, Soft Tissue Sarcomas, soft tissue sardcoma, trabectedin, yondelis


June 27th, 2014

Torisel Improves Event-Free Survival in Rhabdomyosarcoma Patients

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In a study presented at the 2014 American Society of Clinical Oncology® meeting in Chicago, researchers reported that Torisel® (temsirolimus) added to a chemotherapy regimen improved event-free survival in young patients with rhabdomyosarcoma. Rhabdomyosarcoma is a rare cancer that develops in the cells that eventually become skeletal muscles, those used for voluntary movements of the […]

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Tags: News, rhabdomyosarcoma, Sarcoma, Soft Tissue Sarcomas, torisel


September 16th, 2013

End-of-Life Care Remains Aggressive, Despite Patient Wishes

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Although most patients with advanced cancer prefer hospice or palliative care that minimizes symptoms, many continue to receive aggressive treatment during their final weeks and months of life. In fact, elderly patients with advanced cancer often receive intensive treatment until the last month of life and hospice care is often delayed until the final three […]

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Tags: All Cancer Types, Anal Cancer, Bladder Cancer, Bone Cancer, Brain Cancer, Breast Cancer, Cervical Cancer, Colon Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, HIV Related Cancers


September 6th, 2013

Carbon Ion Beam Radiation Effective in Spinal Sarcomas

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Radiation therapy with carbon ions is a safe and effective treatment for people with inoperable spinal sarcomas, according to the results of a study published in Cancer. Sarcomas are a varied group of cancers arising from fibrous tissue, adipose tissue (fat cells), skeletal muscle, smooth muscle, blood vessels, lymph vessels, nervous tissue, mesenchymal cells, bone, […]

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Tags: General Sarcoma, News, Sarcoma


May 15th, 2013

Following Lifestyle Recommendations Reduces Risk of Cancer Death

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People who follow the diet and lifestyle recommendations laid out by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have a 34 percent reduced risk of dying from several diseases and specifically, a 20 percent reduced risk of dying from cancer compared to people who don’t follow the recommendations, […]

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Tags: Anal Cancer, Bladder Cancer, Bone Cancer, Brain Cancer, Breast Cancer, Cervical Cancer, Colon Cancer, Esophageal Cancer, Gastric Cancer, General, Head and Neck Cancer, HIV Related Cancers


February 11th, 2013

Cancer Deaths on the Decline

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Overall cancer death rates continue to decline in both men and women and across major ethnic and racial groups, according to the annual Status of Cancer report published in the Journal of the National Cancer Institute. What’s more—cancer incidence rates for both sexes combined decreased by 1.5 percent per year from 2000 to 2009 and […]

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Tags: Anal Cancer, Bladder Cancer, Bone Cancer, Brain Cancer, Breast Cancer, Cervical Cancer, Colon Cancer, Esophageal Cancer, Gastric Cancer, General, Head and Neck Cancer, HIV Related Cancers


November 1st, 2012

Shorter Chemotherapy Intervals Effective in Ewing Sarcoma

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In patients with localized Ewing sarcoma, chemotherapy administered every two weeks is more effective than chemotherapy administered every three weeks, with no increase in toxicity, according to the results of a study published in the Journal of Clinical Oncology. Ewing sarcoma is a type of cancer that forms in bone or soft tissue. Ewing sarcoma can […]

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Tags: Ewing's Sarcoma Overview, News, Sarcoma