Latest Cancer News

Read the latest cancer news from the National Cancer Institute. The UNM Comprehensive Cancer Center is one of only 49 NCI-designated comprehensive cancer centers bringing leading, national cancer care to New Mexico.

Maintenance Therapy with CC-486 Extends Survival of Adults with AML

Maintenance therapy with CC-486 extended overall survival of adults with the blood cancer acute myeloid leukemia (AML) in a large clinical trial. CC-486 is a pill form of another cancer therapy called azacitidine (Vidaza).

Enfortumab Vedotin Approved for Recurrent Bladder Cancer

Enfortumab vedotin-ejfv (Padcev) has been approved for people with advanced bladder cancer. FDA granted the drug accelerated approval for cancers that have progressed despite previous treatments.

For Metastatic HER2-Positive Breast Cancer, New Treatments Emerge

Tucatinib improved survival for women in the HER2CLIMB trial, including some whose cancer had spread to the brain. Trastuzumab deruxtecan improved survival and shrank many tumors in the DESTINY-Breast01 trial, which led to its accelerated approval.

Brain Cancer Cells Hijack Gene “On Switches” to Drive Tumor Growth

Glioblastoma cells sneak many copies of a key oncogene into circular pieces of DNA. In a new NCI-funded study, scientists found that the cells also slip several different genetic “on switches” into these DNA circles, helping to fuel the cancer’s growth.

New on NCI’s Websites for January 2020

NCI periodically provides updates on new websites and other online content of interest to the cancer community. See selected content that has been added as of January 2020.

Oncofertility: Creating a Bridge Between Cancer Care and Reproductive Health

Dr. Teresa Woodruff discusses the field that connects oncology with reproductive health, and the Oncofertility Consortium’s efforts to support clinicians, cancer patients, and families in understanding how cancer and its treatment affect fertility.

Anal Cancer Incidence and Deaths Are Rising in the United States

The number of cases and deaths from anal cancer have been on the rise in the United States since 2001, according to a new study. The increases have been especially rapid in two segments of the population.

Osimertinib Improves Survival in Advanced Lung Cancer with EGFR Mutations

Osimertinib (Tagrisso) improves survival in people with non-small cell lung cancer with EGFR mutations, updated clinical trial results show. People treated with osimertinib lived longer than those treated with earlier-generation EGFR-targeted drugs.

Surgery for Recurrent Ovarian Cancer Does Not Improve Survival

Secondary surgery for women with recurrent ovarian cancer does not improve how long those women live, findings from a large trial show. The results call into question the current standard of practice for these patients.

Overcoming a Cancer Nemesis? KRAS Inhibitor Shows Promise in Early Trial

An experimental drug, AMG 510, that targets mutated forms of the KRAS protein completely shrank tumors in cancer mouse models and data from a small clinical trial show that it appears to be active against different cancer types with a KRAS mutation.